N-Acyl-1,2,3-triazoles - key intermediates in denitrogenative transformations

被引：6
|
作者：
Motornov, Vladimir [1 ]
Pohl, Radek [1 ]
Klepetarova, Blanka [1 ]
Beier, Petr [1 ]
机构：
[1] Acad Sci Czech Republ, Inst Organ Chem & Biochem, Flemingovo Nam 2, Prague 16610, Czech Republic
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 61期
关键词：
METAL-FREE SYNTHESIS; 1,2,3-TRIAZOLES; TRANSANNULATION; ALKYNES; NH-1,2,3-TRIAZOLES; REACTIVITY; TRIAZOLES; PYRROLES;
D O I：
10.1039/d3cc00987d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Elusive N-acyl-1,2,3-triazoles formed by direct acylation of NH-1,2,3-triazoles were isolated and fully characterized, including X-ray crystallography. A preference for the formation of thermodynamic N2 isomers was established. Direct evidence of interconversion between N1- and N2-acyltriazoles confirmed their value in denitrogenative transformations. Efficient synthesis of enamido triflates from NH-triazoles via the intermediacy of N2-acyl-1,2,3-triazoles was developed.
引用
收藏
页码：9364 / 9367
页数：4
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