N-Acyl-1,2,3-triazoles - key intermediates in denitrogenative transformations

被引：6

作者：

Motornov, Vladimir ^{[1
]}

Pohl, Radek ^{[1
]}

Klepetarova, Blanka ^{[1
]}

Beier, Petr ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Organ Chem & Biochem, Flemingovo Nam 2, Prague 16610, Czech Republic

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 61期

关键词：

METAL-FREE SYNTHESIS; 1,2,3-TRIAZOLES; TRANSANNULATION; ALKYNES; NH-1,2,3-TRIAZOLES; REACTIVITY; TRIAZOLES; PYRROLES;

D O I：

10.1039/d3cc00987d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Elusive N-acyl-1,2,3-triazoles formed by direct acylation of NH-1,2,3-triazoles were isolated and fully characterized, including X-ray crystallography. A preference for the formation of thermodynamic N2 isomers was established. Direct evidence of interconversion between N1- and N2-acyltriazoles confirmed their value in denitrogenative transformations. Efficient synthesis of enamido triflates from NH-triazoles via the intermediacy of N2-acyl-1,2,3-triazoles was developed.

引用

页码：9364 / 9367

页数：4

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