Frailty assessment has come to stay: Retrospective analysis pilot study of two frailty scales in oncological older patients undergoing colorectal surgery

被引:0
|
作者
Garcia-Perez, E. [1 ]
Aguirre-Larracoechea, U. [2 ]
Portugal-Porras, V. [3 ]
Azpiazu-Landa, N. [1 ]
Telletxea-Benguria, S. [1 ]
机构
[1] Galdakao Usansolo Hosp, Dept Anaesthesiol & Intens Care, Galdakao, Vizcaya, Spain
[2] Hosp Galdakao Usansolo, Hlth Serv Res Chron Patients Network, Res Unit, REDISSEC, Galdakao, Vizcaya, Spain
[3] Univ Basque Country, Galdakao Usansolo Hosp, Med & Surg Fac, Gen Surg Dept, Galdakao, Vizcaya, Spain
来源
REVISTA ESPANOLA DE ANESTESIOLOGIA Y REANIMACION | 2023年 / 70卷 / 01期
关键词
Frailty; Cancer; Elderly population; Colorectal surgery; POSTOPERATIVE MORTALITY; PREDICTOR; MORBIDITY; OPTIMIZATION; STATEMENT; SURVIVAL; INDEX;
D O I
10.1016/j.redar.2021.05.028
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Introduction: Colorectal cancer is a disease of the elderly and its main treatment is surgery. Frailty, a clinical syndrome of decreased reserve, increases with age and has been recognized as a predictive factor for postoperative mortality. Our primary objective was to assess the association between twohree frailty scores and mortality. within the first year after surgery, by retrospectively linking frailty scores to mortality data and comparing the strength of their association with mortality to that of the ASA Classification. The frailty scales used were: the Modified Frailty Index (MFI) and, the Risk Analysis Index-A (RAI-A) and the G8 screening test (G8). As secondary objectives, we assessed the relationship of the frailty scales with morbidity and compared all the scales with the ASA. Material and methods: We retrospectively studied 172 patients aged 65 years.and older who underwent laparoscopic colorectal surgery for cancer between January 2017 and June 2018, following them up for 1 year after surgery. Results: Both morbidity and mortality were significantly associated with all frailty scale scores (p < 0.001). The more frailty, the greater probability of prolonged hospital stay, complications, readmissions and emergency department visits. Using each scale, patients were categorized into two groups (frail and non-frail patients). The C-indexes for 1-year mortality with the RAI-A and, MFI and G8 were 0.89 and, 0.86 and 0.86 respectively. On the other hand, ASA status is not strongly associated with mortality, with a C-index of 0.63.Discussion: Frailty scores should begin to influence medical and surgical strategies and further research is needed to develop guidelines for interventions in geriatric patients. (c) 2021 Sociedad Espaniola de Anestesiologi ' a, Reanimacion y Terapeutica del Dolor. Published by Elsevier Espania, S.L.U. All rights reserved.
引用
收藏
页码:1 / 9
页数:9
相关论文
共 46 条
  • [21] Clinical Frailty Score is a good predictor of postoperative mortality in patients undergoing open abdomen surgery: a multicenter retrospective cohort study
    Bunino, Francesca M.
    Marrano, Enrico
    Carbone, Fabio
    Mauri, Giulia
    Ceolin, Martina
    Penazzi, Riccardo
    Zucchini, Nicolas
    Biloslavo, Alan
    Kurihara, Hayato
    MINERVA SURGERY, 2024, 79 (02): : 147 - 154
  • [22] Association of preoperative frailty and postoperative delirium in older cancer patients undergoing elective abdominal surgery: A prospective observational study in Taiwan
    Tsai, Chun-Yi
    Liu, Keng-Hao
    Lai, Cheng-Chou
    Hsu, Jun-Te
    Hsueh, Shun -Wen
    Hung, Chia-Yen
    Yeh, Kun-Yun
    Hung, Yu-Shin
    Lin, Yung -Chang
    Chou, Wen-Chi
    BIOMEDICAL JOURNAL, 2023, 46 (04)
  • [23] Predictive value of frailty assessment tools in patients undergoing surgery for gastrointestinal cancer: An observational cohort study
    Zhang, Hui-Pin
    Zhang, Hai-Lin
    Zhou, Xiao-Min
    Chen, Guan-Jie
    Zhou, Qi-Fan
    Tang, Jie
    Zhu, Zi-Ye
    Wang, Wei
    WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 2023, 15 (11): : 2525 - 2536
  • [24] Postoperative Adverse Outcomes in Patients With Frailty Undergoing Urologic Surgery Among American Patients: A Propensity-Score Matched Retrospective Cohort Study
    Hsu, Cheng-Wei
    Chang, Chuen-Chau
    Lam, Fai
    Liu, Ming-Che
    Yeh, Chun-Chieh
    Chen, Ta-Liang
    Lin, Chao-Shun
    Liao, Chien-Chang
    CLINICAL EPIDEMIOLOGY, 2025, 17 : 241 - 250
  • [25] Usefulness of frailty markers in the assessment of the health and functional status of older cancer patients referred for chemotherapy: A pilot study
    Retornaz, Frederique
    Monette, Johanne
    Batist, Gerald
    Monette, Michele
    Sourial, Nadia
    Small, David
    Caplan, Stephen
    Wan-Chow-Wah, Doreen
    Puts, Martine T. E.
    Bergman, Howard
    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2008, 63 (05): : 518 - 522
  • [26] Measuring the Predictive Accuracy of Preoperative Clinical Frailty Instruments Applied to Electronic Health Data in Older Patients Having Emergency General Surgery A Retrospective Cohort Study
    Grudzinski, Alexa L.
    Aucoin, Sylvie
    Talarico, Robert
    Moloo, Husein
    Lalu, Manoj M.
    McIsaac, Daniel I.
    ANNALS OF SURGERY, 2023, 278 (02) : E341 - E348
  • [27] Influence of Frailty on Outcome in Older Patients Undergoing Non-Cardiac Surgery - A Systematic Review and Meta-Analysis
    Tjeertes, Elke K. M.
    van Fessem, Joris M. K.
    Mattace-Raso, Francesco U. S.
    Hoofwijk, Anton G. M.
    Stolker, Robert Jan
    Hoeks, Sanne E.
    AGING AND DISEASE, 2020, 11 (05): : 1276 - 1290
  • [28] The impact of frailty and sarcopenia on postoperative outcomes in older patients undergoing gastrectomy surgery: a systematic review and meta-analysis
    Yanjiao Shen
    Qiukui Hao
    Jianghua Zhou
    Birong Dong
    BMC Geriatrics, 17
  • [29] Association of preoperative frailty with the risk of postoperative delirium in older patients undergoing hip fracture surgery: a prospective cohort study
    Chunyu Feng
    Haotian Wu
    Ziheng Qi
    Yuzhi Wei
    Bo Yang
    Haolin Yin
    Siyi Yan
    Lu Wang
    Yangyang Yu
    Juanjuan Xie
    Xueyan Xing
    Shumin Tu
    Huan Zhang
    Aging Clinical and Experimental Research, 36
  • [30] Assessment of Frailty Indices and Charlson Comorbidity Index for Predicting Adverse Outcomes in Patients Undergoing Surgery for Spine Metastases: A National Database Analysis
    Elsamadicy, Aladine A.
    Havlik, John L.
    Reeves, Benjamin
    Sherman, Josiah
    Koo, Andrew B.
    Pennington, Zach
    Hersh, Andrew M.
    Sandhu, Mani Ratnesh S.
    Kolb, Luis
    Lo, Sheng-Fu Larry
    Shin, John H.
    Mendel, Ehud
    Sciubba, Daniel M.
    WORLD NEUROSURGERY, 2022, 164 : E1058 - E1070