Imaging of Small-Bowel Neuroendocrine Neoplasms: AJR Expert Panel Narrative Review

被引:6
作者
Navin, Patrick J. [1 ]
Ehman, Eric C. [1 ]
Liu, Jason B. [2 ]
Halfdanarson, Thorvardur R. [3 ]
Gupta, Akshya [4 ]
Laghi, Andrea [5 ]
Yoo, Don C. [6 ]
Carucci, Laura R. [7 ]
Schima, Wolfgang [8 ]
Sheedy, Shannon P. [1 ]
机构
[1] Mayo Clin, Dept Radiol, 200 1st St SW, Rochester, MN 55905 USA
[2] Brigham & Womens Hosp, Dept Surg, Div Surg Oncol, Boston, MA USA
[3] Mayo Clin, Dept Oncol, Div Med Oncol, Rochester, MN USA
[4] Univ Rochester, Dept Imaging Sci, Rochester, NY USA
[5] Sapienza Univ Rome, Dept Med Surg Sci & Translat Med, AOU St Andrea, Rome, Italy
[6] Brown Univ, Warren Alpert Med Sch, Dept Diagnost Imaging, Providence, RI USA
[7] Virginia Commonwealth Univ, Med Ctr, Dept Radiol, Richmond, VA USA
[8] Barmherzige Schwestern Krankenhaus & Sankt Josef, Dept Diagnost & Intervent Radiol, Goettlicher Heiland Krankenhaus, Vienna, Austria
关键词
CT; MRI; neuroendocrine neoplasm; PET; small bowel; GA-68-DOTATATE PET/CT; CARCINOID-TUMORS; GADOXETATE DISODIUM; COMPUTED-TOMOGRAPHY; CAPSULE ENDOSCOPY; LIVER METASTASES; CT-ENTEROGRAPHY; NEEDLE-BIOPSY; DIAGNOSIS; EXPERIENCE;
D O I
10.2214/AJR.22.28877
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Neuroendocrine neoplasms (NENs) of the small bowel are typically slow-growing lesions that remain asymptomatic until reaching an advanced stage. Imaging modalities for lesion detection, staging, and follow-up in patients with known or suspected NEN include CT enterography, MR enterography, and PET/CT using a somatostatin receptor analog. FDG PET/CT may have a role in the evaluation of poorly differentiated NENs. Liver MRI, ideally with a hepatocyte-specific contrast agent, should be used in the evaluation of hepatic metastases. Imaging informs decisions regarding both surgical approaches and systematic therapy (specifically, peptide receptor radionuclide therapy). This AJR Expert Panel Narrative Review describes the multimodality imaging features of small-bowel NENs; explores the optimal imaging modalities for their diagnosis, staging, and follow-up; and discusses how imaging may be used to guide therapy.
引用
收藏
页码:289 / 301
页数:13
相关论文
共 99 条
[1]   Clinical value of 68Ga-DOTATATE-PET/CT compared to stand-alone contrast enhanced CT for the detection of extra-hepatic metastases in patients with neuroendocrine tumours (NET) [J].
Albanus, D. R. ;
Apitzsch, J. ;
Erdem, Z. ;
Erdem, O. ;
Verburg, F. A. ;
Behrendt, F. F. ;
Mottaghy, F. M. ;
Heinzel, A. .
EUROPEAN JOURNAL OF RADIOLOGY, 2015, 84 (10) :1866-1872
[2]   Consensus on molecular imaging and theranostics in neuroendocrine neoplasms [J].
Ambrosini, Valentina ;
Kunikowska, Jolanta ;
Baudin, Eric ;
Bodei, Lisa ;
Bouvier, Catherine ;
Capdevila, Jaume ;
Cremonesi, Marta ;
de Herder, Wouter W. ;
Dromain, Clarisse ;
Falconi, Massimo ;
Fani, Melpomeni ;
Fanti, Stefano ;
Hicks, Rodney J. ;
Kabasakal, Levent ;
Kaltsas, Gregory ;
Lewington, Val ;
Minozzi, Silvia ;
Cinquini, Michela ;
Oberg, Kjell ;
Oyen, Wim J. G. ;
O'Toole, Dermot ;
Pavel, Marianne ;
Ruszniewski, Philippe ;
Scarpa, Aldo ;
Strosberg, Jonathan ;
Sundin, Anders ;
Taieb, David ;
Virgolini, Irene ;
Wild, Damian ;
Herrmann, Ken ;
Yao, James .
EUROPEAN JOURNAL OF CANCER, 2021, 146 :56-73
[3]  
American College of Radiology, 2015, ACR-SAR-SPR practice parameter for the performance of computed tomography (CT) enterography
[4]   Comparison of WHO, RECIST 1.1, EORTC, and PERCIST criteria in the evaluation of treatment response in malignant solid tumors [J].
Aras, Mustafa ;
Erdil, Tanju Y. ;
Dane, Faysal ;
Gungor, Serkan ;
Ones, Tunc ;
Dede, Fuat ;
Inanir, Sabahat ;
Turoglu, Halil T. .
NUCLEAR MEDICINE COMMUNICATIONS, 2016, 37 (01) :9-15
[5]   Severe gastrointestinal bleeding as an early symptom of a malignant carcinoid tumor of the small intestine [J].
Auer, J ;
Kirchgatterer, A ;
Berent, R ;
Allinger, S ;
Hinterholzer, G ;
Höbling, W ;
Meindl, S ;
Oppitz, P ;
Kalchmair, J ;
Neuwirth, G ;
Knoflach, P .
ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2000, 38 (08) :631-+
[6]   MRI of carcinoid tumors: Spectrum of appearances in the gastrointestinal tract and liver [J].
Bader, TR ;
Semelka, RC ;
Chiu, VCY ;
Armao, DM ;
Woosley, JT .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2001, 14 (03) :261-269
[7]   Diagnostic imaging of pancreatic neuroendocrine neoplasms (pNEN): tumor detection, staging, prognosis, and response to treatment [J].
Baur, Alexander D. J. ;
Pavel, Marianne ;
Prasad, Vikas ;
Denecke, Timm .
ACTA RADIOLOGICA, 2016, 57 (03) :260-270
[8]  
Benz C, 1999, Z GASTROENTEROL, V37, P725
[9]   Whole-Body 68Ga-DOTANOC PET/MRI Versus 68Ga-DOTANOC PET/CT in Patients With Neuroendocrine Tumors: A Prospective Study in 28 Patients [J].
Berzaczy, Dominik ;
Giraudo, Chiara ;
Haug, Alexander R. ;
Raderer, Markus ;
Senn, Daniela ;
Karanikas, Georgios ;
Weber, Michael ;
Mayerhoefer, Marius E. .
CLINICAL NUCLEAR MEDICINE, 2017, 42 (09) :669-674
[10]   PET/MRI assessment of lung nodules in primary abdominal malignancies: sensitivity and outcome analysis [J].
Biondetti, Pierpaolo ;
Vangel, Mark G. ;
Lahoud, Rita M. ;
Furtado, Felipe S. ;
Rosen, Bruce R. ;
Groshar, David ;
Canamaque, Lina G. ;
Umutlu, Lale ;
Zhang, Eric W. ;
Mahmood, Umar ;
Digumarthy, Subba R. ;
Shepard, Jo-Anne O. ;
Catalano, Onofrio A. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (06) :1976-1986