Patterns of Electrocardiographic Abnormalities in Children with Hypertrophic Cardiomyopathy

被引：3

作者：

Marshall, Mayme ^{[1
]}

Malik, Aneeq ^{[2
]}

Shah, Maully ^{[3
]}

Fish, Frank A. ^{[4
]}

Etheridge, Susan P. ^{[5
]}

Aziz, Peter F. ^{[1
]}

Russell, Mark W. ^{[6
]}

Tisma, Svjetlana ^{[7
]}

Pflaumer, Andreas ^{[8
]}

Sreeram, Narayanswami ^{[9
]}

Kubus, Peter ^{[10
]}

Law, Ian H. ^{[11
]}

Kantoch, Michal J. ^{[12
]}

Kertesz, Naomi J. ^{[13
]}

Strieper, Margaret ^{[14
]}

Erickson, Christopher C. ^{[15
]}

Moore, Jeremy P. ^{[16
]}

Nakano, Stephanie J. ^{[17
]}

Singh, Harinder R. ^{[18
]}

Chang, Philip ^{[19
]}

Cohen, Mitchell ^{[20
]}

Fournier, Anne ^{[21
]}

Ilina, Maria V. ^{[22
]}

Zimmermann, Frank ^{[23
]}

Horndasch, Michaela ^{[24
]}

Li, Walter ^{[25
]}

Batra, Anjan S. ^{[26
]}

Liberman, Leonardo ^{[27
]}

Hamilton, Robert ^{[28
]}

Janson, Christopher M. ^{[3
]}

Sanatani, Shubhayan ^{[29
]}

Zeltser, Ilana ^{[30
]}

McDaniel, George ^{[31
]}

Blaufox, Andrew D. ^{[32
]}

Garnreiter, Jason M. ^{[33
]}

Balaji, Seshadri ^{[34
]}

机构：

[1] Cleveland Clin Childrens Hosp, Cleveland, OH USA

[2] Univ Los Angeles Olive View, Los Angeles, CA USA

[3] Childrens Hosp Philadelphia, Philadelphia, PA USA

[4] Vanderbilt Univ, Nashville, TN USA

[5] Univ Utah, Salt Lake City, UT USA

[6] CS Mott Childrens Hosp, Ann Arbor, MI USA

[7] Nemours Childrens Hosp, Wilmington, DE USA

[8] Univ Melbourne, Royal Childrens Hosp, Parkville, Vic 3052, Australia

[9] Univ Cologne, Cologne, Germany

[10] Motol Univ, Prague, Czech Republic

[11] Univ Iowa, Iowa City, IA USA

[12] Univ Alberta, Edmonton, AB, Canada

[13] Nationwide Childrens Hosp, Columbus, OH USA

[14] Emory Univ, Childrens Healthcare Atlanta, Atlanta, GA USA

[15] Univ Nebraska Med Ctr, Omaha, NE USA

[16] Univ Calif Los Angeles, Los Angeles, CA USA

[17] Univ Colorado, Denver, CO USA

[18] Baylor Coll Med, Childrens Hosp San Antonio, San Antonio, TX USA

[19] Childrens Mercy Hosp, Kansas City, MO USA

[20] Inova LJ Murphy Childrens Hosp, Falls Church, VA USA

[21] Univ Montreal, Montreal, PQ, Canada

[22] Royal Hosp Childrens, Glasgow, Scotland

[23] Advocate Hosp, Chicago, IL USA

[24] German Heart Ctr, Munich, Germany

[25] Univ Calif San Francisco, San Francisco, CA USA

[26] Univ Calif Irvine, Reseda, CA USA

[27] Columbia Univ, New York, NY USA

[28] Hosp Sick Kids, Toronto, ON, Canada

[29] Univ British Columbia, Vancouver, BC, Canada

[30] Univ Texas Southwestern, Dallas, TX USA

[31] Univ Virginia, Charlottesville, VA USA

[32] Zucker Sch Med Hofstra Northwell, Hempstead, NY USA

[33] St Louis Univ, St Louis, MO USA

[34] Oregon Hlth & Sci Univ, 707 SW Gaines St, Portland, OR 97239 USA

来源：

PEDIATRIC CARDIOLOGY | 2024年 / 45卷 / 08期

关键词：

Hypertrophic cardiomyopathy; Electrocardiogram; Sudden death; Pediatric; Left ventricular hypertrophy; Strain; LEFT-VENTRICULAR HYPERTROPHY; Q-WAVES; DIFFERENTIAL-DIAGNOSIS; AMERICAN-COLLEGE; EUROPEAN-SOCIETY; ECG; ECHOCARDIOGRAPHY; RECOMMENDATIONS; IDENTIFICATION; ACCURACY;

D O I：

10.1007/s00246-023-03252-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypertrophic cardiomyopathy (HCM), a common cardiomyopathy in children, is an important cause of morbidity and mortality. Early recognition and appropriate management are important. An electrocardiogram (ECG) is often used as a screening tool in children to detect heart disease. The ECG patterns in children with HCM are not well described.ECGs collected from an international cohort of children, and adolescents (& LE; 21 years) with HCM were reviewed. 482 ECGs met inclusion criteria. Age ranged from 1 day to 21 years, median 13 years. Of the 482 ECGs, 57 (12%) were normal. The most common abnormalities noted were left ventricular hypertrophy (LVH) in 108/482 (22%) and biventricular hypertrophy (BVH) in 116/482 (24%) Of the patients with LVH/BVH (n = 224), 135 (60%) also had a strain pattern (LVH in 83, BVH in 52). Isolated strain pattern (in the absence of criteria for hypertrophy) was seen in 43/482 (9%). Isolated pathologic Q waves were seen in 71/482 (15%). Pediatric HCM, 88% have an abnormal ECG. The most common ECG abnormalities were LVH or BVH with or without strain. Strain pattern without hypertrophy and a pathologic Q wave were present in a significant proportion (24%) of patients. Thus, a significant number of children with HCM have ECG abnormalities that are not typical for "hypertrophy". The presence of the ECG abnormalities described above in a child should prompt further examination with an echocardiogram to rule out HCM.

引用

页码：1692 / 1701

页数：10

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