Circulating Biomarkers in Coronary Microvascular Dysfunction

被引：11
作者：
Chakrala, Teja [1 ]
Prakash, Roshni [1 ]
Valdes, Carlos [1 ]
Pepine, Carl J. J. [1 ,2 ]
Keeley, Ellen C. C. [1 ,2 ]
机构：
[1] Univ Florida, Dept Med, Gainesville, FL USA
[2] Univ Florida, Div Cardiovasc Med, 1329 SW 16th St,POB 100288, Gainesville, FL 32608 USA
来源：
JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2023年 / 12卷 / 12期
关键词：
biomarker; circulating molecules; coronary microvascular dysfunction; C-REACTIVE PROTEIN; SOLUBLE ADHESION MOLECULES; CARDIAC SYNDROME-X; PLASMA ASYMMETRIC DIMETHYLARGININE; IMPROVES ENDOTHELIAL FUNCTION; HDL CHOLESTEROL RATIO; RHO-KINASE ACTIVITY; ANGINA-PECTORIS; CHEST-PAIN; SYSTEMIC INFLAMMATION;
D O I：
10.1161/JAHA.122.029341
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in the diagnosis and management of coronary microvascular dysfunction. We present an updated review of circulating biomarkers in coronary microvascular dysfunction representing key pathologic processes, including inflammation, endothelial dysfunction, oxidative stress, coagulation, and other mechanisms.
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页数：16
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