Polyvinylpyrrolidone and chitosan-coated magnetite (Fe3O4) nanoparticles for catalytic and antimicrobial activity with molecular docking analysis

被引:72
作者
Ayesha, Muhammad [1 ]
Imran, Muhammad [1 ]
Haider, Ali [2 ]
Shahzadi, Iram [3 ]
Moeen, Sawaira
Ul-Hamid, Anwar [5 ]
Nabgan, Walid [6 ]
Shahzadi, Anum [7 ]
Alshahrani, Thamraa [8 ]
Ikram, Muhammad [4 ]
机构
[1] Govt Coll Univ, Dept Chem, Sahiwal Rd, Sahiwal 57000, Punjab, Pakistan
[2] Muhammad Nawaz Shareef Univ Agr, Fac Vet & Anim Sci, Dept Clin Sci, Multan 66000, Punjab, Pakistan
[3] Univ Punjab, Punjab Univ, Coll Pharm, Lahore 54000, Pakistan
[4] Univ Lahore, Dept Phys, Solar Cell Applicat Res Lab, Govt Coll, Lahore 54000, Punjab, Pakistan
[5] King Fahd Univ Petr & Minerals, Res Inst, Core Res Facil, Dhahran 31261, Saudi Arabia
[6] Univ Rovira i Virgili, Dept Engn Quim, Paisos Catalans 26, Tarragona 43007, Spain
[7] Univ Lahore, Fac Pharm, Lahore 54000, Pakistan
[8] Princess Nourah Bint Abdulrahman Univ PNU, Coll Sci, Dept Phys, POB 84428, Riyadh 11671, Saudi Arabia
来源
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | 2023年 / 11卷 / 03期
关键词
Catalysis; Antibacterial activity; DYE DEGRADATION; ANTIBACTERIAL; EXTRACT; NANOCOMPOSITE; ANTIOXIDANT;
D O I
10.1016/j.jece.2023.110088
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This work presents the synthesis of polyvinylpyrrolidone (PVP) and chitosan (CS) coated magnetite (Fe3O4) nanoparticles (NPs) by co-precipitation technique. The objective of this research was to investigate the catalytic, antibacterial efficacy with evidential molecular docking analysis of CS/PVP- Fe3O4 and PVP/CS- Fe3O4. The coating of PVP and CS reduced the particle size of Fe3O4, providing a large surface area that increased catalytic and antibacterial potency. These binary coated magnetite NPs used as ideal catalytic agent for the reduction of rhodamine B dye as well as antibacterial agent against Escherichia coli. The findings of a molecular docking investigation were in reasonable accord with in vitro microbicidal activity and revealed that CS-Fe3O4, Fe3O4doped PVP and CS are promising inhibitors of dihydrofolate reductaseE. Coli (DHFR) and DNA gyraseE. Coli.
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页数:10
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