Sugar-free synapses run on mitochondrial Sirtuin 3

被引:0
作者
Walsh, Alexander P. [1 ]
Simon, David J. [1 ]
机构
[1] Weill Cornell Med, Dept Biochem, New York, NY 10065 USA
关键词
D O I
10.1083/jcb.202312035
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Metabolic plasticity of neurons ensures their activity continues when glucose is limited. Walsh and Simon discuss new work by Ashrafi and colleagues (https://doi.org/10.1083/jcb.202305048) that finds Sirtuin 3 directs local metabolic adaptation at synapses during sustained glucose deprivation.
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