Breast radiation dose equivalent and cancer risk estimation during PET/ CT examinations

Mammary glands or breasts are radiosensitive organs that makeup 12% of the body's overall radiation sensi-tivity. According to estimates, Saudi Arabia has a 27.3% overall cancer incidence rate for breast cancer. Recent studies reported that breasts get significant organ equivalent doses during diagnostic procedures with ionizing radiation, even though the breast is not the target organ. The objective of this work is to assess the effective and breast equivalent doses during positron emission tomography (PET)/Computed tomography (CT) imaging ex-aminations. The effective and breast equivalent doses per PET/CT (GE PET/CT 710) examination were quantified using the amount of the injected radiopharmaceutical (MBq) (18F-fluorodeoxyglucose (FDG)), and external doses from CT examinations. The average, standard deviation (SD) and range of examined patients' age (years) and body mass index ((BMI), kg/m2) were 58 +/- 11 (39-76) and 30 +/- 5 (20.7-43.1), respectively. Constant administered activity (AA, 185 MBq) and tube potential (120 kVp) were used for all patients. The average, SD, and range of the patients effective dose (mSv) from PET/CT (18F-FDG) examination was 8.0 +/- 0.93 (7.0-10.0) and 2.075 +/- 0.11 (1.91-2.29) in that order. Breast doses are comparable with previous studies during the PET/ CT and mammographic examination. Proper justification criteria and dose optimization are essential to lowering excessive exposure while preserving image quality, especially for young females because they have a higher risk of radiation-induced cancer.