Versatile Design of Organic Polymeric Nanoparticles for Photodynamic Therapy of Prostate Cancer

被引：1

作者：

Ling, Jiacheng ^{[1
,2
]}

Gu, Rongrong ^{[3
,4
]}

Liu, Lulu ^{[5
]}

Chu, Ruixi ^{[3
,4
]}

Wu, Junchao ^{[1
,2
]}

Zhong, Rongfang ^{[1
,2
]}

Ye, Sheng ^{[3
,4
]}

Liu, Jian ^{[6
,7
,8
,9
]}

Fan, Song ^{[1
,2
]}

机构：

[1] Anhui Med Univ, Inst Urol, Dept Urol, Affiliated Hosp 1, Hefei 230022, Peoples R China

[2] Anhui Med Univ, Anhui Prov Key Lab Genitourinary Dis, Hefei 230022, Peoples R China

[3] Anhui Agr Univ, Coll Sci, Hefei 230036, Peoples R China

[4] Anhui Agr Univ, Sch Plant Protect, Hefei 230036, Peoples R China

[5] Anhui Agr Univ, Sch Resources & Environm, Hefei 230036, Peoples R China

[6] Inner Mongolia Univ Hohhot, Hohhot 010021, Inner Mongolia, Peoples R China

[7] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

[8] Univ Surrey, DICP Surrey Joint Ctr Future Mat, Dept Chem & Proc Engn, Guildford GU27XH, Surrey, England

[9] Univ Surrey, Adv Technol Inst, Guildford GU27XH, Surrey, England

来源：

ACS MATERIALS AU | 2023年 / 4卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Photodynamic therapy; Photosensitizer; Organicpolymeric nanoparticles; Prostate cancer; Chemotherapy; Photothermal therapy; Reactive oxygen species; Targeting; PHOTOTHERMAL THERAPY; COMBINATION THERAPY; LIPID-PEROXIDATION; DRUG-DELIVERY; PORPHYRIN; CELLS; HSP90; NANOMEDICINE; MITOCHONDRIA; INHIBITOR;

D O I：

10.1021/acsmaterialsau.3c00060

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Radical prostatectomy is a primary treatment option for localized prostate cancer (PCa), although high rates of recurrence are commonly observed postsurgery. Photodynamic therapy (PDT) has demonstrated efficacy in treating nonmetastatic localized PCa with a low incidence of adverse events. However, its limited efficacy remains a concern. To address these issues, various organic polymeric nanoparticles (OPNPs) loaded with photosensitizers (PSs) that target prostate cancer have been developed. However, further optimization of the OPNP design is necessary to maximize the effectiveness of PDT and improve its clinical applicability. This Review provides an overview of the design, preparation, methodology, and oncological aspects of OPNP-based PDT for the treatment of PCa.

引用

页码：14 / 29

页数：16

共 120 条

[1] Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer [J].

Adiseshaiah, Pavan P. ;

Crist, Rachael M. ;

Hook, Sara S. ;

McNeil, Scott E. .

NATURE REVIEWS CLINICAL ONCOLOGY, 2016, 13 (12) :750-765

[2] Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion [J].

Armstrong, Heather K. ;

Gillis, Joanna L. ;

Johnson, Ian R. D. ;

Nassar, Zeyad D. ;

Moldovan, Max ;

Levrier, Claire ;

Sadowski, Martin C. ;

Chin, Mei Yieng ;

Guns, Emma S. Tomlinson ;

Tarulli, Gerard ;

Lynn, David J. ;

Brooks, Douglas A. ;

Selth, Luke A. ;

Centenera, Margaret M. ;

Butler, Lisa M. .

SCIENTIFIC REPORTS, 2018, 8

[3] Non-canonical anti-cancer, anti-metastatic, anti-angiogenic and immunomodulatory PDT potentials of water soluble phthalocyanine derivatives with imidazole groups and their intracellular mechanism of action [J].

Ayaz, Furkan ;

Yetkin, Derya ;

Yuzer, Abdulcelil ;

Demircioglu, Kubra ;

Ince, Mine .

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2022, 39

[4] Padeliporfi n vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial [J].

Azzouzi, Abdel-Rahmene ;

Vincendeau, Sebastien ;

Barret, Eric ;

Cicco, Antony ;

Kleinclauss, Francois ;

van der Poel, Henk G. ;

Stief, Christian G. ;

Rassweiler, Jens ;

Salomon, Georg ;

Solsona, Eduardo ;

Alcaraz, Antonio ;

Tammela, Teuvo T. ;

Rosario, Derek J. ;

Gomez-Veiga, Francisco ;

Ahlgren, Goran ;

Benzaghou, Fawzi ;

Gaillac, Bertrand ;

Amzal, Billy ;

Debruyne, Frans M. J. ;

Fromont, Gaelle ;

Gratzke, Christian ;

Emberton, Mark .

LANCET ONCOLOGY, 2017, 18 (02) :181-191

[5] Vascular-targeted photodynamic therapy with TOOKADA® Soluble in localized prostate cancer: standardization of the procedure [J].

Azzouzi, Abdel-Rahmene ;

Lebdai, Souhil ;

Benzaghou, Fawzi ;

Stief, Christian .

WORLD JOURNAL OF UROLOGY, 2015, 33 (07) :937-944

[6] 5-Aminolevulinic Acid-Squalene Nanoassemblies for Tumor Photodetection and Therapy: In Vitro Studies [J].

Babic, Andrej ;

Herceg, V. ;

Bastien, E. ;

Lassalle, H. -P. ;

Bezdetnaya, L. ;

Lange, Norbert .

NANOSCALE RESEARCH LETTERS, 2018, 13

[7] Free and Poly-Methyl-Methacrylate-Bounded BODIPYs: Photodynamic and Antimigratory Effects in 2D and 3D Cancer Models [J].

Ballestri, Marco ;

Marras, Emanuela ;

Caruso, Enrico ;

Bolognese, Fabrizio ;

Malacarne, Miryam Chiara ;

Martella, Elisa ;

Tubertini, Matilde ;

Gariboldi, Marzia Bruna ;

Varchi, Greta .

CANCERS, 2023, 15 (01)

[8] Progression-directed Therapy for Oligoprogression in Castration-refractory Prostate Cancer [J].

Berghen, Charlien ;

Joniau, Steven ;

Ost, Piet ;

Poels, Kenneth ;

Everaerts, Wouter ;

Decaestecker, Karel ;

Haustermans, Karin ;

Devos, Gaetan ;

De Meerleer, Gert .

EUROPEAN UROLOGY ONCOLOGY, 2021, 4 (02) :305-309

[9] A Novel Cyanine and Porphyrin Based Theranostic Nanoagent for Near-Infrared Fluorescence Imaging Guided Synergistic Phototherapy [J].

Bhattarai, Pravin ;

Liang, Xiaolong ;

Xu, Yunxue ;

Dai, Zhifei .

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2017, 13 (11) :1468-1479

[10] Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy [J].

Carter, Kevin A. ;

Luo, Dandan ;

Razi, Aida ;

Geng, Jumin ;

Shao, Shuai ;

Ortega, Joaquin ;

Lovell, Jonathan F. .

THERANOSTICS, 2016, 6 (13) :2329-2336

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