ESTIMATION OF GENETIC PARAMETERS FOR SCRAPIE RESISTANCE IN LOCAL BREEDS OF SHEEP RAISED IN ROMANIA

被引:0
|
作者
Paraschivescu, Petrut-Lucian [1 ]
Murshedi, Osamah Mahmood Abdulzahra [1 ]
Grosu, Horia [1 ]
机构
[1] Univ Agron Sci & Vet Med Bucharest, 59 Marasti Blvd,Dist 1, Bucharest, Romania
来源
SCIENTIFIC PAPERS-SERIES D-ANIMAL SCIENCE | 2023年 / 66卷 / 01期
关键词
scrapie; genotype; sanger sequencing; trehold animal model; heritability;
D O I
暂无
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
In the European Union, animal breeding programs have been implemented to increase scrapie resistance in sheep. In addition to increasing animal resistance to an infectious disease, selection for pathogen resistance has the potential to lessen the transmission of the pathogen to offspring, particularly when the population under consideration may serve as the primary pathogen reservoir. Several sheep populations from Romania were used in this study: Tsurcana; Tsigae; Merinos; Cap Negru de Teleorman and some imported breeds: Suffolk; Ille de France and Awassi. Sanger sequencing method was used to identify PRNP genetic polymorphism, at 136, 154 and 171 codons. From the analyzed samples, a moderate share of the homozygous ARR allele, responsible for the highest resistance to scrapie, respectively (R1), was observed, and the heterozygous ARR/ARQ (R2) and homozygous ARQ/ARQ (R3) genotypes had an abundance of over 50% of the genotype panel. In practice, the use of phenotype as input to the model is given by numbers (risk classes from 1 to 5). To estimate the heritability of resistance to scrapie, the animal threshold model was used.
引用
收藏
页码:48 / 51
页数:4
相关论文
共 50 条
  • [31] Estimation of genetic parameters for litter size in Charollais, Romney, Merinolandschaf, Romanov, Suffolk, Sumava and Texel breeds of sheep
    Schmidova, Jitka
    Milerski, Michal
    Svitakova, Alena
    Vostry, Lubos
    Novotna, Alexandra
    SMALL RUMINANT RESEARCH, 2014, 119 (1-3) : 33 - 38
  • [32] Prion protein gene polymorphism and genetic risk evaluation for scrapie in all Turkish native sheep breeds
    H. Meydan
    B. Yüceer
    R. Degirmenci
    M. M. Özkan
    M. A. Yildiz
    Virus Genes, 2012, 45 : 169 - 175
  • [33] Genetic parameters of reproduction traits in German meat and milk sheep breeds
    De Vries, F
    Hamann, H
    Distl, O
    ZUCHTUNGSKUNDE, 2004, 76 (03): : 208 - 220
  • [34] Behaviour characteristics as estimation tool of genetic distance between sheep breeds
    Handiwirawan, E.
    Noor, R. R.
    Sumantri, C.
    Subandriyo
    JURNAL ILMU TERNAK DAN VETERINER, 2014, 19 (04) : 239 - 247
  • [35] Prion protein gene polymorphism and genetic risk evaluation for scrapie in all Turkish native sheep breeds
    Meydan, H.
    Yuceer, B.
    Degirmenci, R.
    Ozkan, M. M.
    Yildiz, M. A.
    VIRUS GENES, 2012, 45 (01) : 169 - 175
  • [36] Estimation of genetic parameters for reproduction traits In sheep
    Savas, T
    Röhe, R
    Kalm, E
    ZUCHTUNGSKUNDE, 2000, 72 (03): : 217 - 229
  • [37] Estimation of genetic parameters for reproductive indices in sheep
    Senes, Beatriz Bastos
    da Cruz, Valdecy Aparecida Rocha
    Azevedo, Hymerson Costa
    Costa, Raphael Bermal
    de Camargo, Gregorio Miguel Ferreira
    JOURNAL OF ANIMAL BREEDING AND GENETICS, 2024, 141 (05) : 485 - 490
  • [38] EVALUATION OF GENETIC RESISTANCE TO HAEMONCHUS CONTORTUS INFECTION IN PAKISTANI SHEEP BREEDS
    Babar, M. E.
    Hussain, T.
    Abdullah, M.
    Ali, A.
    Nadeem, A.
    Kamran, Z.
    Ali, M. M.
    JOURNAL OF ANIMAL AND PLANT SCIENCES, 2013, 23 (05): : 1219 - 1222
  • [39] GENETIC-MARKERS IN HERDWICK SHEEP - NO CORRELATION WITH SUSCEPTIBILITY OR RESISTANCE TO EXPERIMENTAL SCRAPIE
    COLLIS, SC
    MILLSON, GC
    KIMBERLIN, RH
    ANIMAL BLOOD GROUPS AND BIOCHEMICAL GENETICS, 1977, 8 (02): : 79 - 83
  • [40] Genetic analysis of CSN2 in local and international cattle breeds raised in Poland
    Barlowska, Joanna
    Sawicka-Zugaj, Wioletta
    Slaska, Brygida
    Krol, Jolanta
    Brodziak, Aneta
    Teter, Anna
    Chabuz, Witold
    ANIMAL SCIENCE PAPERS AND REPORTS, 2022, 40 (04): : 411 - 422