Meningovascular Syphilis: A Case of a Young Man Presenting With Acute Stroke and Pulmonary Emboli

被引:0
作者
Ragusa, Alexa [1 ]
Kapustka, Adrian [2 ]
Ganti, Latha [2 ]
Gue, Shayne [1 ]
机构
[1] Univ Cent Florida, HCA, Emergency Med, Florida Healthcare Grad Med Educ GME, Kissimmee, FL 32827 USA
[2] Univ Cent Florida, Coll Med, Emergency Med, Orlando, FL USA
关键词
pulmonary embolism; hiv; stroke; neurosyphilis; meningovascular syphilis; syphilis; NEUROSYPHILIS;
D O I
10.7759/cureus.44568
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Syphilis is caused by the spirochete Treponema pallidum and classically progresses through a series of stages with increasing symptomatology if unrecognized and untreated. Importantly, central nervous system invasion can occur at any stage, which can lead to variable presentations of neurosyphilis. One such manifestation is meningovascular syphilis, which causes thrombosis of the cerebral vasculature, leading to stroke-like symptoms such as hemiplegia and aphasia. Young, healthy patients may present with these symptoms without any risk factors typically associated with the pathophysiology of cerebrovascular accidents. Further, patients living with HIV who present with stroke-like symptoms should have an even higher suspicion for neurosyphilis as a potential diagnosis. We present a case report of a 31-year-old male with sudden left-sided weakness and numbness who tested positive for both Treponema pallidum and human immunodeficiency virus (HIV).
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相关论文
共 11 条
[1]  
[Anonymous], 2023, Sexually transmitted diseases
[2]  
[Anonymous], 2021, Sexually Transmitted Disease Surveillance 2019, DOI DOI 10.15620/CDC.79370
[3]   Neurosyphilis: A Historical Perspective and Review [J].
Ghanem, Khalil G. .
CNS NEUROSCIENCE & THERAPEUTICS, 2010, 16 (05) :e157-e168
[4]   Evaluation and management of syphilis in the HIV-infected patient [J].
Ghanem K.G. .
Current Infectious Disease Reports, 2010, 12 (2) :140-146
[5]   State-of-the-Art Review: Neurosyphilis [J].
Hamill, Matthew M. ;
Ghanem, Khalil G. ;
Tuddenham, Susan .
CLINICAL INFECTIOUS DISEASES, 2024, 78 (05) :e57-e68
[6]  
Hobbs Emily, 2018, Pract Neurol, V18, P211, DOI [10.1136/practneurol-2017-001754, 10.1136/practneurol-2017-001754]
[7]   Autopsy case of acute pulmonary thromboembolism with neurosyphilis [J].
Kondo T. ;
Takahashi M. ;
Kuse A. ;
Morichika M. ;
Nakagawa K. ;
Sakurada M. ;
Asano M. ;
Ueno Y. .
Egyptian Journal of Forensic Sciences, 8 (1)
[8]   Neurosyphilis presenting as acute ischemic stroke [J].
Krishnan, Dhayalen ;
Zaini, Siti S. M. ;
Latif, Kartikasalwah A. ;
Joseph, Joyce P. .
CLINICAL MEDICINE, 2020, 20 (01) :95-97
[9]   Meningovascular neurosyphilis with basilar artery thrombosis in HIV patient [J].
Perez Barragan, Edgar ;
Urdez Hernandez, Elena ;
Perez Orozco, Bernardo ;
Sanchez Gonzalez, Mariela .
JOURNAL OF INFECTION AND PUBLIC HEALTH, 2018, 11 (03) :439-441
[10]   The Intersection of HIV and Syphilis: Update on the Key Considerations in Testing and Management [J].
Ren, Melody ;
Dashwood, Thomas ;
Walmsley, Sharon .
CURRENT HIV/AIDS REPORTS, 2021, 18 (04) :280-288