Does Music Intervention Improve Anxiety in Dementia Patients? A Systematic Review and Meta-Analysis of Randomized Controlled Trials

被引：6

作者：

Ting, Berne ^{[1
,2
]}

Chen, Daniel Tzu-Li ^{[2
,3
,4
,5
]}

Hsu, Wei-Ti ^{[5
,6
]}

Liang, Chih-Sung ^{[7
]}

Malau, Ikbal Andrian ^{[2
,5
]}

Li, Wei-Chih ^{[2
,8
]}

Lee, Sheau-Ling ^{[9
]}

Jingling, Li ^{[5
]}

Su, Kuan-Pin ^{[2
,5
,10
]}

机构：

[1] China Med Univ, Coll Med, Ph D Program Aging, Taichung 40402, Taiwan

[2] China Med Univ Hosp, Mind Body Interface Lab, MBI Lab, Taichung 40402, Taiwan

[3] China Med Univ, Coll Med, Taichung 40402, Taiwan

[4] China Med Univ, Coll Chinese Med, Sch Chinese Med, Taichung 40402, Taiwan

[5] China Med Univ, Grad Inst Biomed Sci, Coll Med, Taichung 40402, Taiwan

[6] China Med Univ Hosp, Dept Anesthesiol, Taichung 40402, Taiwan

[7] Triserv Gen Hosp, Natl Def Med Ctr, Beitou Branch, Taipei 11490, Taiwan

[8] China Med Univ, Coll Med, Sch Med, Taichung 40402, Taiwan

[9] Natl Hlth Res Inst, Miaoli 35053, Taiwan

[10] China Med Univ, Annan Hosp, Tainan 70965, Taiwan

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 17期

关键词：

anxiety; Alzheimer's disease; dementia; music intervention; music therapy; MILD COGNITIVE IMPAIRMENT; QUALITY-OF-LIFE; ALZHEIMERS-DISEASE; NERVOUS-SYSTEM; PSYCHOLOGICAL SYMPTOMS; REDUCE ANXIETY; OLDER-PEOPLE; NEURAL BASIS; THERAPY; DISORDERS;

D O I：

10.3390/jcm12175497

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Music interventions (MIs) have been widely used to relieve anxiety in dementia in clinical settings. However, limited meta-analysis with randomized controlled trials (RCTs) on this topic has been conducted so far. A systematic search was conducted in four major databases (PubMed, EMBASE, Web of Science, and Cochrane Library) for data provided by RCTs from the inception to February 2023. The search strategy employed the terms "anxiety AND music AND dementia OR Alzheimer's disease". Thirteen RCTs (827 participants) were included. The results showed MI reduced anxiety significantly (SMD = -0.67, p < 0.001), especially for Alzheimer's disease (p = 0.007) and Mixed (p < 0.001)-type dementia. Moreover, significant improvements in agitation (p = 0.021) and depression (p < 0.001) in dementia were observed. Additionally, several psychological mechanisms which may be associated with MI were reviewed comprehensively. In conclusion, our findings support the efficacy of MI in alleviating anxiety symptoms in dementia patients. PROSPERO Registration (ID: CRD42021276646).

引用

页数：16

共 100 条

[21] Effect of a non-pharmacological intervention, Voix d'Or®, on behavior disturbances in Alzheimer disease and associated disorders [J].