Effect of extracted rice protein hydrolysate on high -fat diet induced obesity in mice

被引：0
作者：
Matsumoto, Yu [1 ,3 ]
Iwasaki, Yu [2 ]
Hosokawa, Megumi [2 ]
Suzuki, Tsukasa [1 ]
Inoue, Jun [1 ]
Shigemura, Yasutaka [2 ]
Takano, Katsumi [1 ]
Yamamoto, Yuji [1 ]
机构：
[1] Tokyo Univ Agr, Fac Appl Biosci, Dept Agr Chem, Setagaya Ku, 1-1-1 Sakuragaoka, Tokyo 1560054, Japan
[2] Tokyo Kasei Univ, Fac Domest Sci, Dept Nutr, Itabashi Ku, 1-18-1 Kaga, Tokyo 1738602, Japan
[3] Komazawa Womens Univ, Dept Hlth & Nutr Sci, 238 Sakahama, Inagi shi, Tokyo 2068511, Japan
来源：
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 2023年 / 70卷 / 05期
关键词：
extracted rice protein hydrolysate; anti; -obesity; peptide; free amino acid; PRECOLUMN DERIVATIZATION; LIVER-DISEASE; IN-VITRO; GLYCINE; IDENTIFICATION; METABOLISM; ACTIVATION; PEPTIDES;
D O I：
10.3136/nskkk.NSKKK-D-22-00090
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
We investigated the effect of extracted rice protein hydrolysate (ERP), a byproduct of low -protein rice, for use as a therapeutic diet for kidney disease patients. The ERP was composed mostly of peptides and free amino acids. Administering ERP inhibited the body mass compared to obese model mice fed a high -fat diet. ERP administration also significantly increased and decreased fecal triglycerides and epididymal adipose tissue weight, respectively. Blood alanine aminotransferase levels decreased, indicating that hepatic inflammation was reduced. Also, a decrease in ceramide synthase 6, which is related to insulin resistance, was observed. Since ERP was composed mostly of peptides and free amino acids, we hypothesize that the observed effects were due to peptides and/or free amino acids. Based on the findings, ERP is a very useful anti -obesity food additive.
引用
收藏
页码：177 / 185
页数：9
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