The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023

被引：150

作者：

Wang, Feng-Hua ^{[1
]}

Zhang, Xiao-Tian ^{[2
]}

Tang, Lei ^{[3
]}

Wu, Qi ^{[4
]}

Cai, Mu-Yan ^{[5
]}

Li, Yuan-Fang ^{[6
]}

Qu, Xiu-Juan ^{[7
]}

Qiu, Hong ^{[8
]}

Zhang, Yu-Jing ^{[9
]}

Ying, Jie-Er ^{[10
]}

Zhang, Jun ^{[11
]}

Sun, Ling-Yu ^{[12
]}

Lin, Rong-Bo ^{[13
]}

Wang, Chang ^{[14
]}

Liu, Hao ^{[15
]}

Qiu, Miao-Zhen ^{[1
]}

Guan, Wen-Long ^{[1
]}

Rao, Sheng-Xiang ^{[16
]}

Ji, Jia-Fu ^{[17
]}

Xin, Yan ^{[18
]}

Sheng, Wei-Qi ^{[19
]}

Xu, Hui-Mian ^{[20
]}

Zhou, Zhi-Wei ^{[21
]}

Zhou, Ai-Ping ^{[22
]}

Jin, Jing ^{[23
]}

Yuan, Xiang-Lin ^{[24
]}

Bi, Feng ^{[25
]}

Liu, Tian-Shu ^{[26
]}

Liang, Han ^{[27
]}

Zhang, Yan-Qiao ^{[28
]}

Li, Guo-Xin ^{[15
]}

Liang, Jun ^{[29
]}

Liu, Bao-Rui ^{[30
]}

Shen, Lin ^{[31
]}

Li, Jin ^{[32
]}

Xu, Rui-Hua ^{[1
]}

机构：

[1] Sun Yat Sen Univ Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Radiat Oncol, State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China

[2] Peking Univ Canc Hosp & Inst, Minist Educ, Key Lab Carcinogenesis & Translat Res, Dept Gastrointestinal Oncol, Beijing, Peoples R China

[3] Peking Univ Canc Hosp, Dept Pathol, Beijing, Peoples R China

[4] Peking Univ Canc Hosp, Dept Endoscopy Ctr, Beijing, Peoples R China

[5] Sun Yat Sen Univ Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Hematol Oncol, State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China

[6] Sun Yat Sen Univ Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Gastr Surg, State Key Lab Oncol South China, Guangzhou 510060, Guangdong, Peoples R China

[7] First Hosp China Med Univ, Dept Pathol, Shenyang, Liaoning, Peoples R China

[8] Huazhong Univ Sci & Technol, Affiliated Tongji Hosp, Tongji Med Coll, Dept Ultrasonog, Wuhan, Hubei, Peoples R China

[9] Sun Yat Sen Univ, State Key Lab Oncol South China, Collaborat Innovat Ctr Canc Med, Dept Gen,Canc Ctr, Guangzhou, Guangdong, Peoples R China

[10] Zhejiang Canc Hosp, Dept Med Oncol, Hangzhou, Zhejiang, Peoples R China

[11] Shanghai Jiaotong Univ Sch Med, Ruijin Hosp, Dept Radiat Oncol, Shanghai, Peoples R China

[12] Fourth Affiliated Hosp Harbin Med Univ, Dept Obstet & Gynecol, Harbin, Heilongjiang, Peoples R China

[13] Fujian Canc Hosp, Dept Pathol, Fuzhou, Fujian, Peoples R China

[14] First Hosp Jilin Univ, Tumor Ctr, Changchun, Jilin, Peoples R China

[15] Southern Med Univ, Nanfang Hosp, Dept Gen Surg, Guangzhou, Guangdong, Peoples R China

[16] Fudan Univ, Zhongshan Hosp, Dept Radiol, Shanghai, Peoples R China

[17] Peking Univ Canc Hosp, Dept Gastrointestinal Surg, Beijing, Peoples R China

[18] China Med Univ, Gastrointestinal Tumor Pathol Lab, Inst Canc, Hosp 1, Shenyang 110001, Liaoning, Peoples R China

[19] Fudan Univ, Affiliated Zhongshan Hosp, Dept Geriatr, Shanghai, Peoples R China

[20] First Hosp China Med Univ, Dept Surg Oncol, Shenyang, Liaoning, Peoples R China

[21] Sun Yat Sen Univ Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Gastr Surg, State Key Lab Oncol South China, Guangzhou 510060, Guangdong, Peoples R China

[22] Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Natl Clin Res Ctr Canc, Dept Radiat Oncol,Canc Hosp, Beijing, Peoples R China

[23] Chinese Acad Med Sci, Shenzhen Hosp, Canc Hosp, Shenzhen, Peoples R China

[24] Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Oncol, Affiliated Tongji Hosp, Wuhan, Hubei, Peoples R China

[25] Sichuan Univ, West China Hosp, Dept Abdominal Oncol, Chengdu, Sichuan, Peoples R China

[26] Fudan Univ, Affiliated Zhongshan Hosp, Dept Geriatr, Shanghai, Peoples R China

[27] Tianjin Med Univ Canc Inst & Hosp, Dept Gastr Surg, Tianjin, Peoples R China

[28] Harbin Med Univ, Dept Med Oncol, Canc Hosp, Harbin, Heilongjiang, Peoples R China

[29] Peking Univ, Int Hosp, Dept Med Oncol, Beijing, Peoples R China

[30] Nanjing Univ, Nanjing Drum Tower Hosp, Dept Pathol, Affiliated Hosp ,Med Sch, Nanjing, Peoples R China

[31] Peking Univ Canc Hosp & Inst, Dept GI Oncol, Minist Educ, Key Lab Carcinogenesis & Translat Res, Beijing 100142, Peoples R China

[32] Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China

来源：

CANCER COMMUNICATIONS | 2023年

关键词：

Chinese Society of Clinical Oncology (CSCO); gastric cancer; diagnosis; surgery; neoadjuvant; adjuvant; radiotherapy; chemotherapy; targeted therapy; immunotherapy; PHASE-III TRIAL; LYMPH-NODE DISSECTION; GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA; INTENSITY-MODULATED RADIOTHERAPY; ENDOSCOPIC SUBMUCOSAL DISSECTION; 3-DIMENSIONAL CONFORMAL RADIOTHERAPY; STEREOTACTIC BODY RADIOTHERAPY; CAPECITABINE PLUS OXALIPLATIN; INVOLVED-FIELD RADIOTHERAPY; RANDOMIZED CONTROLLED-TRIAL;

D O I：

10.1002/cac2.12516

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The 2023 update of the Chinese Society of Clinical Oncology (CSCO) Clinical Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China, reflecting the latest advancements in evidence-based medicine, healthcare resource availability, and precision medicine. These updates address the differences in epidemiological characteristics, clinicopathological features, tumor biology, treatment patterns, and drug selections between Eastern and Western gastric cancer patients. Key revisions include a structured template for imaging diagnosis reports, updated standards for molecular marker testing in pathological diagnosis, and an elevated recommendation for neoadjuvant chemotherapy in stage III gastric cancer. For advanced metastatic gastric cancer, the guidelines introduce new recommendations for immunotherapy, anti-angiogenic therapy and targeted drugs, along with updated management strategies for human epidermal growth factor receptor 2 (HER2)-positive and deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) patients. Additionally, the guidelines offer detailed screening recommendations for hereditary gastric cancer and an appendix listing drug treatment regimens for various stages of gastric cancer. The 2023 CSCO Clinical Guidelines for Gastric Cancer updates are based on both Chinese and international clinical research and expert consensus to enhance their applicability and relevance in clinical practice, particularly in the heterogeneous healthcare landscape of China, while maintaining a commitment to scientific rigor, impartiality, and timely revisions.

引用

页码：127 / 172

页数：46

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