Supercharging metabolic health with Lycium barbarum L.: A review of the therapeutic potential of this functional food for managing metabolic syndrome

被引：4

作者：

Sharifi-Rad, Javad ^{[1
,16
]}

Quetglas-Llabres, Maria Magdalena ^{[2
,3
]}

Sureda, Antoni ^{[2
,3
,4
]}

Mardones, Lorena ^{[5
]}

Villagran, Marcelo ^{[5
,6
]}

Gurer, Eda Sonmez ^{[6
]}

Zivkovic, Jelena ^{[7
]}

Ezzat, Shahira M. ^{[8
,9
]}

Zayed, Ahmed ^{[10
]}

Gumusok, Safa ^{[11
]}

Kilic, Ceyda Sibel ^{[10
]}

Fasipe, Babatunde ^{[12
]}

Laher, Ismail ^{[13
]}

Martorell, Miquel ^{[14
,15
]}

机构：

[1] Univ Azuay, Fac Med, Cuenca, Ecuador

[2] Univ Balear Isl IUNICS, Res Grp Community Nutr & Oxidat Stress, Palma De Mallorca, Mallorca, Spain

[3] Univ Balear Isl IUNICS, Hlth Res Inst Balear Isl IdISBa, Palma De Mallorca, Mallorca, Spain

[4] Inst Salud Carlos III, CIBEROBN Physiopathol Obes & Nutr, Madrid, Spain

[5] Univ Catolica Santisima Concepcion, Fac Med, Dept Basic Sci, Concepcion, Chile

[6] Univ Catolica Santisima Concepcion, Sci Technol Ctr Sustainable Dev Coastline, Concepcion, Chile

[7] Inst Med Plant Res Dr Josif Pancic, Tadeusa Koscuska 1, Belgrade, Serbia

[8] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Cairo, Egypt

[9] October Univ Modern Sci & Arts MSA, Fac Pharm, Dept Pharmacognosy, 6th Of October, Egypt

[10] Tanta Univ, Coll Pharm, Dept Pharmacognosy, Tanta 8130, Egypt

[11] Ankara Univ, Fac Pharm, Dept Pharmaceut Bot, Ankara, Turkiye

[12] Bowen Univ, Fac Basic Med Sci, Dept Pharmacol & Therapeut, Iwo, Nigeria

[13] Univ British Columbia, Fac Med, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC, Canada

[14] Univ Concepcion, Fac Pharm, Dept Nutr & Dietet, Concepcion, Chile

[15] Univ Concepcion, Ctr Hlth Living, Concepcion, Chile

[16] Shahid Beheshti Univ Med Sci, Phytochem Res Ctr, Tehran, Iran

来源：

FOOD FRONTIERS | 2024年 / 5卷 / 02期

关键词：

goji; immune system; Lycium barbarum; metabolic syndrome; oxidative stress; polysaccharides; INDUCED OXIDATIVE STRESS; HYPOGLYCEMIC ACTIVITY; GUT MICROBIOTA; GOJI BERRY; POLYSACCHARIDES; ANTIOXIDANT; FRUIT; PATHOPHYSIOLOGY; MODULATION; EXTRACTION;

D O I：

10.1002/fft2.327

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Metabolic syndrome (MetS) is a common disorder involving a cluster of metabolic abnormalities, such as abdominal obesity, hypertension, dyslipidemia, insulin resistance, and atherogenic profile. MetS is characterized by an increase in oxidative stress and a chronic proinflammatory state, which are directly related to the development and progression of this pathology. It has been seen how a healthy lifestyle and good dietary practices are key to improving the different metabolic parameters and, therefore, play a fundamental role in reducing the risk of developing diabetes. The present review focuses on the research evidence related to the therapeutic properties of Lycium barbarum L. in MetS gathered in the last years. Several preclinical studies suggest that L. barbarum extracts are a good dietary supplement for the prevention of cardiovascular diseases in people with MetS. This compound has been used for years in traditional Chinese medicine for the treatment of atrophic gastritis, problems related to the lungs, kidneys, and liver, and as a supplement for eye health. In addition, different in vitro and in vivo studies have been carried out that support the properties attributed to metabolites derived from L. barbarum, such as polysaccharides that have been shown diverse biological activities. In conclusion, L. barbarum extracts have multiple benefits to increase general well-being and immune function. However, there are a limited number of studies related to effect of L. barbarum in MetS, but they demonstrated effectiveness in the treatment of obesity, diabetes mellitus type 2, and prevention of diabetes mellitus type 2 complication.

引用

页码：420 / 434

页数：15

共 112 条

[1] Goji Berries Supplementation in the Diet of Rabbits and Other Livestock Animals: A Mini-Review of the Current Knowledge [J].