Anti-inflammatory Activities of Sulfated Polysaccharides From Ethanol Crude Extract of Spyrida Species Red Seaweed

Introduction: The extracts derived from red seaweed have shown characteristics that may reduce inflammation. The abovementioned effects can potentially provide positive outcomes in managing inflammatory illnesses, including arthritis, inflammatory bowel disease, and other skin problems.Aim: The polysaccharides were isolated from the Spyrida species. The water-soluble polysaccharides were extracted and fractionated from several Indian seaweeds (Red) using a simple, cost-effective approach. Anti-inflammatory effects were further evaluated and validated by FTIR and FESEM analyses.Materials and methods: FT-IR and FESEM were used to assess the structural features of polysaccharides and the surface morphology. In addition, the red seaweed species of the genus Spyrida, which includes polysaccharides, was shown to significantly inhibit the denaturation of bovine serum albumin (BSA), further proving that the substance has anti-inflammatory qualities.Results: In this work, an assay to suppress protein activity was utilized to investigate the potential anti-inflammatory effects of polysaccharides derived from Spyrida. As predicted, increasing concentrations of the extract, ranging from 25 to 100 mu g/ml, led to a rise in the percentage of inhibited protein denaturation.Conclusion: A statistically significant difference was found between these findings and those obtained with aspirin, a commonly used non-steroidal anti-inflammatory medicine (NSAID). The red algae that grow in the shallow waters of the southern Indian Ocean may be used in medicine.