Advances in the Modifications of 4-Monosubstituted 1,2,3-Triazoles

被引：1

作者：

Yang Baomin ^{[1
]}

Zhang Shuitao ^{[1
]}

Dong Xian ^{[2
]}

Qin Guiping ^{[1
]}

Jiang Yubo ^{[1
]}

机构：

[1] Kunming Univ Sci & Technol, Fac Sci, Kunming 650500, Yunnan, Peoples R China

[2] Yunnan Univ Chinese Med, Coll Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China

来源：

ACTA CHIMICA SINICA | 2023年 / 81卷 / 11期

基金：

中国国家自然科学基金;

关键词：

AZIDE-ALKYNE CYCLOADDITION; AZA-MICHAEL ADDITION; C-H AMINATION; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; CLICK CHEMISTRY; 4,5-DISUBSTITUTED 2H-1,2,3-TRIAZOLES; 2,4-DISUBSTITUTED 1,2,3-TRIAZOLES; FACILE SYNTHESIS; TRIAZOLES;

D O I：

10.6023/A23060284

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1,2,3-Triazole is a kind of 5-membered N-heterocycle widely applied in pharmaceutical, pesticide and materials. 1,2,3-Trizole chemistry has stepped into a new era in the fields of organic synthesis and pharmacochemistry since the Cu-catalyzed azide-alkyne dipolar cycloaddition was founded by the Sharpless and Meldal groups in 2002. 4-Monosubstituted 1,2,3-triazole is a noble member in its family owing to the structural merits of facile modifications, leading to novel molecules. The transformations of 4-monosubstituted 1,2,3-triazoles basing on different reaction sites including the N-1, N-2 and N-3 are reviewed. The substrate scope, limitation, and representative mechanism are also discussed.

引用

页码：1577 / 1589

页数：13

共 101 条

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