Immune-active polymeric materials for the treatment of inflammatory diseases

被引：2
作者：
Lazar, Kat M. [1 ]
Shetty, Shamitha [1 ]
Chilkoti, Ashutosh [1 ]
Collier, Joel H. [1 ]
机构：
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
来源：
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2023年 / 67卷
基金：
美国国家卫生研究院;
关键词：
Immunoengineering; Polymer biomaterials; Inflammation; Autoimmunity; BIOMATERIALS; RESPONSES; INNATE; HYDROPHOBICITY; NANOPARTICLES; MACROPHAGES; STRATEGIES; THERAPIES; VACCINES; TNF;
D O I：
10.1016/j.cocis.2023.101726
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
In recent years, a growing understanding of the underlying mechanisms of autoinflammatory and autoimmune disease has enabled significant advances in biomaterial therapeutics for their treatment and prevention. Drug-free or immune-active polymeric materials are of particular interest due to their chemical tunability, multifaceted mechanisms of action, and potential to offer alternatives to conventional treatments. While in many cases the relationships between polymer physicochemical properties and the immune processes they influence are context-dependent and require further clarity, several concepts are emerging that can be applied in the design of anti-inflammatory materials. This review highlights recent work that investigates these relationships, as well as work that applies them to immunomodulatory biomaterials for the treatment or prevention of autoimmune and autoinflammatory diseases.
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页数：18
相关论文
共 78 条
[1]   Hyaluronic Acid: Redefining Its Role [J].
Abatangelo, G. ;
Vindigni, V. ;
Avruscio, G. ;
Pandis, L. ;
Brun, P. .
CELLS, 2020, 9 (07) :1-19
[2]   Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine [J].
Andorko, James I. ;
Jewell, Christopher M. .
BIOENGINEERING & TRANSLATIONAL MEDICINE, 2017, 2 (02) :139-155
[3]   Introduction of Non-natural Amino Acids Into T-Cell Epitopes to Mitigate Peptide-Specific T-Cell Responses [J].
Azam, Aurelien ;
Mallart, Sergio ;
Illiano, Stephane ;
Duclos, Olivier ;
Prades, Catherine ;
Maillere, Bernard .
FRONTIERS IN IMMUNOLOGY, 2021, 12
[4]  
Badylak SF, 2021, IMMUNOMODULATORY BIO
[5]   Biomaterial-mediated modification of the local inflammatory environment [J].
Browne, Shane ;
Pandit, Abhay .
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2015, 3
[6]   Advanced nanomedicines for the treatment of inflammatory diseases [J].
Brusini, Romain ;
Varna, Mariana ;
Couvreur, Patrick .
ADVANCED DRUG DELIVERY REVIEWS, 2020, 157 :161-178
[7]   Curing inflammatory diseases using phosphorous dendrimers [J].
Caminade, Anne-Marie ;
Turrin, Cedric-Olivier ;
Poupot, Remy .
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2022, 14 (04)
[8]   Unexpected In Vivo Anti-Inflammatory Activity Observed for Simple, Surface Functionalized Poly(amidoamine) Dendrimers [J].
Chauhan, Abhay S. ;
Diwan, Prakash V. ;
Jain, Narenda K. ;
Tomalia, Donald A. .
BIOMACROMOLECULES, 2009, 10 (05) :1195-1202
[9]   Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies [J].
Chen, Bing-Mae ;
Cheng, Tian-Lu ;
Roffler, Steve R. .
ACS NANO, 2021, 15 (09) :14022-14048
[10]   The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation [J].
Chen, Jianjun ;
Pompano, Rebecca R. ;
Santiago, Felix W. ;
Maillat, Lea ;
Sciammas, Roger ;
Sun, Tao ;
Han, Huifang ;
Topham, David J. ;
Chong, Anita S. ;
Collier, Joel H. .
BIOMATERIALS, 2013, 34 (34) :8776-8785
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