Canine thyroid carcinomas: A review with emphasis on comparing the compact subtype of follicular thyroid carcinomas and medullary thyroid carcinomas

被引:6
作者
Athey, Jillian M. [1 ]
Vieson, Miranda D. [1 ,3 ]
Bailey, Keith [2 ]
Rudmann, Dan [2 ]
Baumgartner, Wes A. [1 ]
Selting, Kim A. [1 ]
机构
[1] Univ Illinois, Urbana, IL USA
[2] Charles River Labs, Mattawan, MI USA
[3] Univ Illinois, 1224 Vet Med Basic Sci Bldg,2001 South Lincoln Ave, Urbana, IL 61802 USA
关键词
canine; carcinoma; follicular adenocarcinoma; dogs; medullary carcinoma; thyroid; IMMUNOHISTOCHEMICAL DETECTION; PROGNOSTIC-FACTORS; DOGS; CALCITONIN; THYROGLOBULIN; THERAPY; TUMORS; PATHWAY;
D O I
10.1177/03009858231177225
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Canine thyroid carcinomas are relatively common malignant endocrine neoplasms in dogs derived from either thyroid follicular cells (forming follicular thyroid carcinomas) or medullary cells (parafollicular, C-cells; forming medullary thyroid carcinomas). Older and recent clinical studies often fail to discriminate between compact cellular (solid) follicular thyroid carcinomas and medullary thyroid carcinomas, which may skew conclusions. The compact subtype of follicular thyroid carcinomas appears to be the least differentiated subtype of follicular thyroid carcinomas and needs to be differentiated from medullary thyroid carcinomas. This review includes information on the signalment, presentation, etiopathogenesis, classification, histologic and immunohistochemical diagnosis, clinical management, and biochemical and genetic derangements of canine follicular and medullary carcinomas, and their correlates with human medicine.
引用
收藏
页码:7 / 19
页数:13
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