Risk factors for dementia in Brazil: Differences by region and race

被引：37

作者：

Suemoto, Claudia K. ^{[1
]}

Mukadam, Naaheed ^{[2
]}

Brucki, Sonia M. D. ^{[3
]}

Caramelli, Paulo ^{[4
]}

Nitrini, Ricardo ^{[3
]}

Laks, Jerson ^{[5
]}

Livingston, Gill ^{[2
]}

Ferri, Cleusa P. ^{[6
,7
]}

机构：

[1] Univ Sao Paulo, Fac Med, Div Geriatr, Sao Paulo, Brazil

[2] UCL, Div Psychiat, London, England

[3] Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo, Brazil

[4] Univ Fed Minas Gerais, Dept Internal Med, Fac Med, Belo Horizonte, MG, Brazil

[5] Univ Fed Rio de Janeiro, Dept Psychiat, Rio De Janeiro, Brazil

[6] Hosp Alemao Oswaldo Cruz, Hlth Technol Assessment Unit, Sao Paulo, Brazil

[7] Univ Fed Sao Paulo, Dept Psychiat, Escola Paulista Med, Sao Paulo, Brazil

来源：

ALZHEIMERS & DEMENTIA | 2023年 / 19卷 / 05期

关键词：

dementia; epidemiology; prevention; risk factors; HEARING-LOSS; ALZHEIMERS-DISEASE; LATIN-AMERICA; POPULATION; PREVENTION; PREVALENCE; INTERVENTION; IMPAIRMENT; ADULTS;

D O I：

10.1002/alz.12820

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction Twelve risk factors (RFs) account for 40% of dementia cases worldwide. However, most data for population attributable fractions (PAFs) are from high-income countries (HIC). We estimated how much these RFs account for dementia cases in Brazil, stratifying estimates by race and socioeconomic level. Methods We calculated the prevalence and communalities of 12 RFs using 9412 Brazilian Longitudinal Study of Aging participants, then stratified according to self-reported race and country macro-regions. Results The overall weighted PAF was 48.2%. Less education had the largest PAF (7.7%), followed by hypertension (7.6%), and hearing loss (6.8%). PAF was 49.0% and 54.0% in the richest and poorest regions, respectively. PAFs were similar among White and Black individuals (47.8% and 47.2%, respectively) but the importance of the main RF varied by race. Discussion Brazil's potential for dementia prevention is higher than in HIC. Education, hypertension, and hearing loss should be priority targets.

引用

页码：1849 / 1857

页数：9

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