DICER1-Altered Extraovarian Moderately Differentiated Sertoli-Leydig Cell Tumor: Report of a Rare Case

被引：2

作者：

Lau, Joseph C. C. ^{[1
]}

McCluggage, W. Glenn ^{[7
]}

Yuen, Liz Y. P. ^{[2
]}

Shing, Matthew M. K. ^{[3
]}

Chan, Godfrey C. F. ^{[3
,6
]}

Yam, Felix S. D. ^{[5
]}

Leung, Michael W. Y. ^{[5
]}

Ng, Wai-Fu ^{[4
]}

Liu, Anthony P. Y. ^{[3
,6
,8
]}

机构：

[1] Hong Kong Childrens Hosp, Dept Paediat & Adolescent Med, Hong Kong, Peoples R China

[2] Hong Kong Childrens Hosp, Dept Pathol, Div Genet & Genom Pathol, Hong Kong, Peoples R China

[3] Hong Kong Childrens Hosp, Dept Paediat & Adolescent Med, Hong Kong, Peoples R China

[4] Hong Kong Childrens Hosp, Dept Pathol, Div Anat Pathol, Hong Kong, Peoples R China

[5] Hong Kong Childrens Hosp, Dept Surg, Hong Kong, Peoples R China

[6] Univ Hong Kong, Dept Paediat & Adolescent Med, Hong Kong, Peoples R China

[7] Belfast Hlth & Social Care Trust, Dept Pathol, Belfast, North Ireland

[8] Queen Mary Hosp, Dept Paediat & Adolescent Med, Room 115,1-F,New Clin Bldg,102 Pokfulam Rd, Hong Kong, Peoples R China

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY | 2023年 / 42卷 / 04期

关键词：

Sertoli-Leydig cell tumor; Sex-cord stromal tumor; Extraovarian; DICER1; OVARIAN; PROLIFERATIONS; MUTATIONS;

D O I：

10.1097/PGP.0000000000000902

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We report an unusual case of a pelvic extraovarian moderately differentiated Sertoli-Leydig cell tumor arising in a 4-yr-old female. The tumor contained a DICER1 pathogenic variant which was absent in the germline ruling out DICER1 syndrome. In reporting this case, we discuss the differential diagnosis and possible histogenesis and review reported cases of extraovarian Sertoli-Leydig cell tumor.

引用

页码：421 / 425

页数：5

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