The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors

被引：117

作者：

Alexander, Stephen P. H. ^{[1
]}

Fabbro, Doriano ^{[2
]}

Kelly, Eamonn ^{[3
]}

Mathie, Alistair A. ^{[4
]}

Peters, John A. ^{[5
]}

Veale, Emma L. ^{[6
]}

Armstrong, Jane F. ^{[7
]}

Faccenda, Elena ^{[7
]}

Harding, Simon D. ^{[7
]}

Davies, Jamie A. ^{[7
]}

Beuve, Annie ^{[8
]}

Brouckaert, Peter ^{[9
]}

Bryant, Clare ^{[10
]}

Burnett, John C. ^{[11
]}

Farndale, Richard W. ^{[10
]}

Friebe, Andreas ^{[12
]}

Garthwaite, John ^{[13
]}

Hobbs, Adrian J. ^{[14
]}

Jarvis, Gavin E. ^{[15
]}

Koesling, Doris ^{[16
]}

Kuhn, Michaela ^{[12
]}

Macewan, David ^{[17
]}

Monie, Tom P. ^{[10
]}

Potter, Lincoln R. ^{[18
]}

Russwurm, Michael ^{[16
]}

Schmidt, Harald H. H. W. ^{[19
]}

Stasch, Johannes-Peter ^{[20
]}

Waldman, Scott A. ^{[21
]}

机构：

[1] Univ Nottingham, Sch Life Sci, Med Sch, Nottingham NG7 2UH, England

[2] PIQUR Therapeut, CH-4057 Basel, Switzerland

[3] Univ Bristol, Sch Physiol Pharmacol & Neurosci, Bristol BS8 1TD, England

[4] Univ Suffolk, Sch Allied Hlth Sci, Ipswich IP4 1QJ, England

[5] Univ Dundee, Ninewells Hosp & Med Sch, Med Educ Inst, Dundee DD1 9SY, Scotland

[6] Univ Greenwich & Kent Medway, Medway Sch Pharm, Anson Bldg,Cent Ave, Chatham ME4 4TB, Kent, England

[7] Univ Edinburgh, Ctr Discovery Brain Sci, Edinburgh EH8 9XD, Scotland

[8] New Jersey Med Sch Rutgers, Newark, NJ USA

[9] Univ Ghent, Ghent, Belgium

[10] Univ Cambridge, Cambridge, England

[11] Mayo Clin, Rochester, MN USA

[12] Univ Wurzburg, Wurzburg, Germany

[13] UCL, London, England

[14] Queen Mary Univ London, London, England

[15] Univ Sunderland, Sunderland, England

[16] Ruhr Univ Bochum, Bochum, Germany

[17] Univ Liverpool, Liverpool, England

[18] Univ Minnesota, Minneapolis, MN USA

[19] Maastricht Univ, Maastricht, Netherlands

[20] Bayer HealthCare, Wuppertal, Germany

[21] Thomas Jefferson Univ, Philadelphia, PA USA

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 2023年 / 180卷

关键词：

D O I：

10.1111/bph.16180

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and nearly 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at . Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

引用

页码：S241 / S288

页数：48