Selective Laser Sintering for printing pharmaceutical dosage forms

被引：26

作者：

Tabriz, Atabak Ghanizadeh ^{[2
]}

Kuofie, Hannah ^{[1
]}

Scoble, James ^{[1
]}

Boulton, Sam ^{[1
]}

Douroumis, Dennis ^{[1
,2
,3
]}

机构：

[1] Univ Greenwich, Fac Engn & Sci, Medway Campus,Chatham Maritime, Chatham ME4 4TB, Kent, England

[2] Delta Pharmaceut Ltd, Chatham ME4 5NG, Kent, England

[3] Univ Greenwich, Medway Sch Sci, Medway Campus,Chatham Maritime, Chatham ME4 4TB, Kent, England

来源：

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY | 2023年 / 86卷

关键词：

Selective laser sintering; 3D printing; Manufacturing; Personalised; Medicines; Decentralised; Oral; Polymers; MECHANICAL-PROPERTIES; BEHAVIOR; FABRICATION; PARAMETERS; COMPONENTS; SYSTEMS; POWDERS;

D O I：

10.1016/j.jddst.2023.104699

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Three-dimensional (3D) printing has revolutionised the field of pharmaceutical manufacturing due to the unique capabilities to tailor the dosage forms properties and overcome constrains of conventional technologies. There is a plurality of 3D printing techniques that offer flexibility on the shape, geometry, active(s) dose and dissolution rates for improved patient treatment. Over the last few years selective laser sintering (SLS) has captured research interest for the development of innovative drug products. SLS possess technological features that can transform medicine manufacturing from one-size-fits-all to personalised dosage forms with improved clinical outcomes, patient acceptability, and adherence. Moreover, SLS has the capacity to pave the way for decentralised manufacturing and introduce new supply chain models with reduce complexity. In this review we present the technological features, manufacturing challenges, advantages and limitations of SLS for manufacturing medicines.

引用

页数：13

共 57 条

[1] Understanding the effects of formulation and process variables on the printlets quality manufactured by selective laser sintering 3D printing [J].

Ali, Sogra F. Barakh ;

Mohamed, Eman M. ;

Ozkan, Tanil ;

Kuttolamadom, Mathew A. ;

Khan, Mansoor A. ;

Asadi, Amir ;

Rahman, Ziyaur .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 570

[2] 3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology [J].

Awad, Atheer ;

Fina, Fabrizio ;

Trenfield, Sarah J. ;

Patel, Pavanesh ;

Goyanes, Alvaro ;

Gaisford, Simon ;

Basit, Abdul W. .

PHARMACEUTICS, 2019, 11 (04)

[3] The effect of processing conditions on the mechanical properties of polyethylene produced by selective laser sintering [J].

Bai, Jiaming ;

Zhang, Baicheng ;

Song, Jie ;

Bi, Guijun ;

Wang, Pan ;

Wei, Jun .

POLYMER TESTING, 2016, 52 :89-93

[4] Ceramic components manufacturing by selective laser sintering [J].

Bertrand, Ph. ;

Bayle, F. ;

Combe, C. ;

Goeuriot, P. ;

Smurov, I. .

APPLIED SURFACE SCIENCE, 2007, 254 (04) :989-992

[5]

Campbell T, 2011, APPL LEGAL PHILOS, P1

[6] Dependence of mechanical properties of polyamide components on build parameters in the SLS process [J].

Caulfield, B. ;

McHugh, P. E. ;

Lohfeld, S. .

JOURNAL OF MATERIALS PROCESSING TECHNOLOGY, 2007, 182 (1-3) :477-488

[7] The usefulness of stereomodels in maxillofacial surgical management [J].

Chow, Lop Keung ;

Cheung, Lim Kwong .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2007, 65 (11) :2260-2268

[8] Direct metal laser sintering (DMLS) of a customized titanium mesh for prosthetically guided bone regeneration of atrophic maxillary arches [J].

Ciocca, L. ;

Fantini, M. ;

De Crescenzio, F. ;

Corinaldesi, G. ;

Scotti, R. .

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2011, 49 (11) :1347-1352

[9]

Crump S.S., 1989, APPARATUS METHOD CRE, DOI [10.2116/bunsekikagaku.28.3_195, DOI 10.2116/BUNSEKIKAGAKU.28.3_195]

[10] Current formulation approaches in design and development of solid oral dosage forms through three-dimensional printing [J].

Curti, Carlo ;

Kirby, Daniel J. ;

Russell, Craig A. .

PROGRESS IN ADDITIVE MANUFACTURING, 2020, 5 (02) :111-123

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