Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study

被引：10

作者：

El Naamani, Kareem ^{[1
]}

Mastorakos, Panagiotis ^{[1
]}

Adeeb, Nimer ^{[2
]}

Lan, Mathews ^{[1
]}

Castiglione, James ^{[1
]}

Khanna, Omaditya ^{[1
]}

Diestro, Jose Danilo Bengzon ^{[3
,4
]}

McLellan, Rachel M. ^{[5
,6
]}

Dibas, Mahmoud ^{[3
,4
,5
,6
]}

Vranic, Justin E. ^{[5
,6
]}

Aslan, Assala ^{[2
]}

Cuellar-Saenz, Hugo H. ^{[2
]}

Guenego, Adrien ^{[7
]}

Carnevale, Joseph ^{[8
]}

Saliou, Guillaume ^{[9
]}

Ulfert, Christian ^{[10
]}

Mohlenbruch, Markus ^{[10
]}

Foreman, Paul M. ^{[11
]}

Vachhani, Jay A. ^{[11
]}

Hafeez, Muhammad U. ^{[12
,13
]}

Waqas, Muhammad ^{[14
]}

Tutino, Vincent M. ^{[14
]}

Rabinov, James D. ^{[5
,6
]}

Ren, Yifan ^{[15
]}

Michelozzi, Caterina ^{[16
]}

Spears, Julian ^{[3
,4
]}

Panni, Pietro ^{[17
]}

Griessenauer, Christoph J. ^{[18
,19
]}

Asadi, Hamed ^{[15
]}

Regenhardt, Robert W. ^{[5
,6
]}

Stapleton, Christopher J. ^{[5
,6
]}

Ghozy, Sherief ^{[5
,6
]}

Siddiqui, Adnan ^{[14
]}

Patel, Nirav J. ^{[5
,6
]}

Kan, Peter ^{[12
,13
]}

Boddu, Srikanth ^{[8
]}

Knopman, Jared ^{[8
]}

Aziz-Sultan, Mohammad A. ^{[5
,6
]}

Zanaty, Mario ^{[1
]}

Ghosh, Ritam ^{[1
]}

Abbas, Rawad ^{[1
]}

Amllay, Abdelaziz ^{[1
]}

Tjoumakaris, Stavropoula I. ^{[1
]}

Gooch, Michael R. ^{[1
]}

Cancelliere, Nicole M. ^{[3
,4
]}

Herial, Nabeel A. ^{[1
]}

Rosenwasser, Robert H. ^{[1
]}

Zarzour, Hekmat ^{[1
]}

Schmidt, Richard F. ^{[1
]}

Pereira, Vitor Mendes ^{[3
,4
]}

机构：

[1] Thomas Jefferson Univ Hosp, Dept Neurol Surg, Philadelphia, PA USA

[2] Louisiana State Univ, Dept Neurosurg & Neurointervent Surg, Shreveport, LA USA

[3] Univ Toronto, St Michaels Hosp, Neurovasc Ctr, Dept Med Imaging, Toronto, ON, Canada

[4] Univ Toronto, St Michaels Hosp, Neurovasc Ctr, Dept Neurosurg, Toronto, ON, Canada

[5] Harvard Med Sch, Massachusetts Gen Hosp, Neuroendovasc Program, Boston, MA 02115 USA

[6] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA

[7] Hop Univ Erasme, Serv Neuroradiol Intervent, Brussels, Belgium

[8] New York Presbyterian Hosp, Weill Cornell Sch Med, Neurosurg & Intervent Neuroradiol, New York, NY USA

[9] Ctr Hosp Vaudois Lausanne, Serv Radiodiagnost & Radiol Intervent, Lausanne, Switzerland

[10] Univ Klinikum Heidelberg, Sekt Vaskulare & Intervent Neuroradiol, Heidelberg, Germany

[11] Orlando Hlth Neurosci & Rehabil Inst, Neurosurg Dept, Orlando, FL USA

[12] UTMB, Dept Neurosurg, Houston, TX USA

[13] Baylor Sch Med, Houston, TX USA

[14] SUNY Buffalo, Dept Neurosurg, Buffalo, NY USA

[15] Austin Hlth, Dept Radiol, Intervent Radiol & Neurointervent Serv, Melbourne, Vic, Australia

[16] Osped Niguarda Ca Granda, Interventist Neurovascolare, Milan, Italy

[17] San Raffaele Univ Hosp, Intervent Neuroradiol & Neurosurg, Milan, Italy

[18] Paracelsus Med Univ Salzburg, Christian Doppler Univ Hosp, Dept Neurosurg, Salzburg, Austria

[19] Paracelsus Med Univ, Inst Neurointervent, Salzburg, Austria

来源：

TRANSLATIONAL STROKE RESEARCH | 2024年 / 15卷 / 03期

关键词：

WEB device; Imaging; Positive predictive value; Obliteration; Aneurysm; ENDOVASCULAR TREATMENT;

D O I：

10.1007/s12975-023-01153-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 +/- 11.9 years were studied. The mean neck diameter and height were 3.9 +/- 1.3 mm and 6.0 +/- 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 +/- 1.8 and 14.1 +/- 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.

引用

页码：591 / 598

页数：8