Role of the microbiota-gut-brain axis in postacute COVID syndrome

被引：11

作者：

Gareau, Melanie G. ^{[1
]}

Barrett, Kim E. ^{[2
]}

机构：

[1] Univ Calif Davis, Sch Vet Med, Davis, CA 95616 USA

[2] Univ Calif Davis, Sch Med, Sacramento, CA USA

来源：

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY | 2023年 / 324卷 / 04期

基金：

美国国家卫生研究院;

关键词：

cognitive function; COVID-19; microbiota-gut-brain; PASC; SARS-CoV-2; GASTROINTESTINAL SYMPTOMS; DYNAMICS;

D O I：

10.1152/ajpgi.00293.2022

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The COVID-19 pandemic has resulted in the infection of hundreds of millions of individuals over the past 3 years, coupled with millions of deaths. Along with these more acute impacts of infection, a large subset of patients has developed symptoms that collectively comprise "postacute sequelae of COVID-19" (PASC, also known as long COVID), which can persist for months and maybe even years. In this review, we outline the current knowledge on the role of impaired microbiota-gut-brain (MGB) axis signaling in the development of PASC and the potential mechanisms involved, which may lead to a better understanding of disease progression and treatment options in the future.

引用

页码：G322 / G328

页数：7

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