[1] Newcastle Univ, Translat & Clin Res Inst, Fac Med Sci, Newcastle Upon Tyne NE4 5PL, England
[2] Univ Warwick, Dept Comp Sci, Coventry CV4 7EZ, England
[3] Newcastle Upon Tyne Hosp NHS Fdn Trust, Newcastle Upon Tyne NE7 7DN, England
[4] Newcastle Univ, Natl Inst Hlth & Care Res NIHR, Newcastle Biomed Res Ctr BRC, Newcastle Upon Tyne NE1 7RU, England