Aortitis Associated with Prophylactic Short-acting Granulocyte Colony-stimulating Factor Administration: A Case Report and Review of the Literature

被引:3
作者
Masuda, Yasutaka
Oyama, Takashi
Nakazaki, Kumi
Nakai, Yudai
Sasaki, Ken
Matsuda, Kensuke
Masamoto, Yosuke
Kurokawa, Mineo [1 ]
机构
[1] Univ Tokyo, Grad Sch Med, Dept Hematol & Oncol, Tokyo, Japan
关键词
granulocyte colony-stimulating factor; short-acting G-CSF; long-acting G-CSF; aortitis; prophylactic treatment; non-Hodgkin lymphoma; DAILY FILGRASTIM; OPEN-LABEL; CHEMOTHERAPY; PEGFILGRASTIM; NEUTROPENIA; RECOMMENDATIONS; LYMPHOMA;
D O I
10.2169/internalmedicine.0599-22
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We herein report an 83-year-old woman with filgrastim-associated aortitis during chemotherapy for re-lapsed diffuse large B-cell lymphoma. She had been treated with filgrastim as a prophylaxis for neutropenia during the fourth cycle of chemotherapy from day 9 to 18. On day 21, she developed a fever. Contrast -enhanced computed tomography revealed aortitis of the descending aorta. The fever abated with non-steroidal anti-inflammatory drug treatment. A literature review identified a small number of aortitis cases all caused by prophylactic use of granulocyte colony-stimulating factors (G-CSFs), among which short-acting filgrastim was rarely encountered. The present and previous findings imply a possible relationship between aortitis and prophylactic G-CSF usage.
引用
收藏
页码:1647 / 1652
页数:6
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