Comparison of clinical categories, blood biomarkers and cycle threshold value in COVID-19

被引:0
作者
Yapici, Oktay [1 ]
Oksuzoglu, Muhhamet [1 ]
Yilmaz, Ayse [1 ]
Camlik, Ezgi [2 ]
Unlu, Mehmet [3 ]
机构
[1] Balikesir Univ, Dept Infect Dis & Clin Microbiol, Balikesir, Turkiye
[2] Balikesir Univ, Dept Publ Hlth, Balikesir, Turkiye
[3] Balikesir Univ, Fac Med, Dept Microbyol, Balikesir, Turkiye
来源
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE | 2023年 / 14卷 / 01期
关键词
Cycle Threshold; COVID-19; Biomarkers;
D O I
10.4328/ACAM.21450
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim: The aim of this study is to investigate whether the viral load of SARS-CoV-2 is an important factor in predicting disease severity and its relationship with clinical and biochemical parameters.Material and Methods: In this cross-sectional retrospective study, 85 patients who were found to be positive for SARS-CoV-2 PCR at Balikesir University Health Practice and Research Hospital were evaluated. RT-PCR (CT) values, laboratory values and demographic and clinical data of the patients at the first admission to the hospital were obtained from the electronic environment and compared.Results: In our study, no significant relationship was found between baseline values and severity of clinical stages in adults with COVID-19. No correlation was found between the gender, vital status, hospitalization or admission to the intensive care unit, presence of comorbidity, degree of disease according to the thorax CT image and mean CT values of the participants included in the study (p>0.05).Discussion: More prospective studies and additional data are needed to determine whether CT values can benefit clinicians in clinical and patient management decisions.
引用
收藏
页码:75 / 77
页数:3
相关论文
共 15 条
  • [1] Alsaeedi H, 2021, FRONT MED-LAUSANNE, V8, P1
  • [2] Cycle threshold values in RT-PCR to determine dynamics of SARS-CoV-2 viral load: An approach to reduce the isolation period for COVID-19 patients
    Aranha, Clara
    Patel, Vainav
    Bhor, Vikrant
    Gogoi, Dimpu
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (12) : 6794 - 6797
  • [3] Atique M, 2021, CUREUS J MED SCIENCE, V27, P1
  • [4] The association of viral load and disease severity in children with COVID-19
    Aykac, Kubra
    Yayla, Burcu Ceylan Cura
    Ozsurekci, Yasemin
    Evren, Kubra
    Oygar, Pembe Derin
    Gurlevik, Sibel Lacinel
    Coskun, Tugce
    Tasci, Onur
    Kaya, Filiz Demirel
    Fidanci, Ilknur
    Tasar, Medine Aysin
    Alp, Alpaslan
    Cengiz, Ali Bulent
    Karahan, Sevilay
    Ceyhan, Mehmet
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (05) : 3077 - 3083
  • [5] Early Predictors of Clinical Deterioration in a Cohort of 239 Patients Hospitalized for Covid-19 Infection in Lombardy, Italy
    Cecconi, Maurizio
    Piovani, Daniele
    Brunetta, Enrico
    Aghemo, Alessio
    Greco, Massimiliano
    Ciccarelli, Michele
    Angelini, Claudio
    Voza, Antonio
    Omodei, Paolo
    Vespa, Edoardo
    Pugliese, Nicola
    Parigi, Tommaso Lorenzo
    Folci, Marco
    Danese, Silvio
    Bonovas, Stefanos
    [J]. JOURNAL OF CLINICAL MEDICINE, 2020, 9 (05)
  • [6] Chen W., 2021, COMPUT MATHEMATICL M, V2021, P1
  • [7] Aging in COVID-19: Vulnerability, immunity and intervention
    Chen, Yiyin
    Klein, Sabra L.
    Garibaldi, Brian T.
    Li, Huifen
    Wu, Cunjin
    Osevala, Nicole M.
    Li, Taisheng
    Margolick, Joseph B.
    Pawelec, Graham
    Leng, Sean X.
    [J]. AGEING RESEARCH REVIEWS, 2021, 65
  • [8] COVID-19 Viral Load in the Severity of and Recovery From Olfactory and Gustatory Dysfunction
    Cho, Ryan H. W.
    To, Zion W. H.
    Yeung, Zenon W. C.
    Tso, Eugene Y. K.
    Fung, Kitty S. C.
    Chau, Sandy K. Y.
    Leung, Erica Y. L.
    Hui, Thomas S. C.
    Tsang, Steven W. C.
    Kung, K. N.
    Chow, Eudora Y. D.
    Abdullah, Victor
    van Hasselt, Andrew
    Tong, Michael C. F.
    Ku, Peter K. M.
    [J]. LARYNGOSCOPE, 2020, 130 (11) : 2680 - 2685
  • [9] SARS-CoV-2 PCR cycle threshold at hospital admission associated with patient mortality
    Choudhuri, Jui
    Carter, Jamal
    Nelson, Randin
    Skalina, Karin
    Osterbur-Badhey, Marika
    Johnston, Andrew
    Goldstein, Doctor
    Paroder, Monika
    Szymanski, James
    [J]. PLOS ONE, 2020, 15 (12):
  • [10] Imam Z, 2020, J INTERN MED, V288, P469, DOI 10.1111/joim.13119