Pulmonary Mycobacterium abscessus infection treated in combination with inhaled tigecycline

被引：1
作者：
Pedersen, Andreas Arnholdt [1 ,2 ,3 ]
Floe, Andreas [4 ]
Lokke, Anders [1 ,2 ]
Hilberg, Ole [1 ,2 ,3 ]
机构：
[1] Lillebaelt Hosp, Dept Pulm Res, Vejle, Denmark
[2] Univ Southern Denmark, Dept Reg Hlth Res, Odense, Denmark
[3] Mycobacterial Ctr Res Southern Denmark, Odense, Denmark
[4] Aarhus Univ Hosp, Dept Resp Dis & Allergy, Aarhus, Denmark
来源：
BMJ CASE REPORTS | 2023年 / 16卷 / 12期
关键词：
Infectious diseases; TB and other respiratory infections; Respiratory medicine; Drugs: infectious diseases; DISEASE;
D O I：
10.1136/bcr-2023-255383
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pulmonary disease caused by Mycobacterium abscessus is difficult to treat, as there is currently no reliable evidence-based treatment. Treatment is long, complex and has many side effects. In this case, we report a patient with treatment-refractory pulmonary M. abscessus disease, treated with inhaled tigecycline. Treatment with inhaled tigecycline lasted 15 months with comparably limited side effects. There were no positive mycobacterial cultures in the follow-up period of 2 years. Inhaled tigecycline is an option in the treatment of pulmonary M. abscessus when first-line treatment fails. Additional research should investigate this further.
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