Traditional herbs: mechanisms to combat cellular senescence

被引：0

作者：

Wang, Lei ^{[1
,2
]}

Wang, Jiahui ^{[2
]}

Yang, Zhihui ^{[2
]}

Wang, Yue ^{[2
]}

Zhao, Tiejian ^{[3
]}

Luo, Weisheng ^{[4
]}

Liang, Tianjian ^{[2
]}

Yang, Zheng ^{[2
]}

机构：

[1] Guangxi Univ Chinese Med, Grad Sch, Nanning 530222, Guangxi, Peoples R China

[2] Guangxi Univ Chinese Med, Dept Med, Fac Chinese Med Sci, Nanning 530222, Guangxi, Peoples R China

[3] Guangxi Univ Chinese Med, Coll Basic Med, Dept Physiol, Nanning 530222, Guangxi, Peoples R China

[4] Guangxi Univ Chinese Med, Ruikang Hosp, Nanning, Guangxi, Peoples R China

来源：

AGING-US | 2023年 / 15卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Chinese herbal medicine; cellular senescence; inflammatory response; intestinal flora; GINSENOSIDE RG1 PROTECTS; ENDOTHELIAL PROGENITOR CELLS; ISCHEMIA-REPERFUSION INJURY; NRF2 SIGNALING PATHWAY; CHAIN FATTY-ACIDS; NF-KAPPA-B; OXIDATIVE STRESS; INDUCED APOPTOSIS; STEM-CELLS; IN-VIVO;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cellular senescence plays a very important role in the ageing of organisms and age-related diseases that increase with age, a process that involves physiological, structural, biochemical and molecular changes in cells. In recent years, it has been found that the active ingredients of herbs and their natural products can prevent and control cellular senescence by affecting telomerase activity, oxidative stress response, autophagy, mitochondrial disorders, DNA damage, inflammatory response, metabolism, intestinal flora, and other factors. In this paper, we review the research information on the prevention and control of cellular senescence in Chinese herbal medicine through computer searches of PubMed, Web of Science, Science Direct and CNKI databases.

引用

页码：14473 / 14505

页数：33

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