Safety and efficacy of CD22 and CD19 CAR-T bridging auto-HSCT as consolidation therapy for AYA and adult B-ALL

被引：4
作者：
Qiu, Yan [1 ,2 ]
Wan, Chao-Ling [1 ,2 ]
Xu, Ming-Zhu [1 ,2 ]
Zhou, Hai-Xia [1 ,2 ]
Liu, Mei-Jing [1 ,2 ]
Gong, Wen-Jie [1 ,2 ]
Kang, Li-Qing [3 ]
Sun, Ai-Ning [1 ,2 ]
Yu, Lei [3 ,4 ]
Wu, De-Pei [1 ,2 ]
Qian, Chong-Sheng [1 ,2 ]
Xue, Sheng-Li [1 ,2 ]
机构：
[1] Soochow Univ, Jiangsu Inst Hematol, Natl Clin Res Ctr Hematol Dis, Affiliated Hosp 1, Suzhou, Peoples R China
[2] Soochow Univ, Inst Blood & Marrow Transplantat, Collaborat Innovat Ctr Hematol, Suzhou 215000, Peoples R China
[3] Shanghai Unicar Therapy Biomed Technol Co Ltd, Shanghai, Peoples R China
[4] East China Normal Univ, Inst Biomed Engn & Technol, Shanghai Engn Res Ctr Mol Therapeut & New Drug Dev, Sch Chem & Mol Engn, Shanghai, Peoples R China
来源：
BLOOD CANCER JOURNAL | 2023年 / 13卷 / 01期
基金：
中国国家自然科学基金;
关键词：
ACUTE LYMPHOBLASTIC-LEUKEMIA; CELL THERAPY;
D O I：
10.1038/s41408-023-00837-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：4
相关论文
共 15 条
[1]   Preparing for CAR T cell therapy: patient selection, bridging therapies and lymphodepletion [J].
Amini, Leila ;
Silbert, Sara K. ;
Maude, Shannon L. ;
Nastoupil, Loretta J. ;
Ramos, Carlos A. ;
Brentjens, Renier J. ;
Sauter, Craig S. ;
Shah, Nirali N. ;
Abou-El-Enein, Mohamed .
NATURE REVIEWS CLINICAL ONCOLOGY, 2022, 19 (05) :342-355
[2]   Status of minimal residual disease determines outcome of autologous hematopoietic SCT in adult ALL [J].
Giebel, S. ;
Stella-Holowiecka, B. ;
Krawczyk-Kulis, M. ;
Goekbuget, N. ;
Hoelzer, D. ;
Doubek, M. ;
Mayer, J. ;
Piatkowska-Jakubas, B. ;
Skotnicki, A. B. ;
Dombret, H. ;
Ribera, J. M. ;
Piccaluga, P. P. ;
Czerw, T. ;
Kyrcz-Krzemien, S. ;
Holowiecki, J. .
BONE MARROW TRANSPLANTATION, 2010, 45 (06) :1095-1101
[3]   Hematopoietic stem cell transplantation for adults with Philadelphia chromosome-negative acute lymphoblastic leukemia in first remission: a position statement of the European Working Group for Adult Acute Lymphoblastic Leukemia (EWALL) and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT) [J].
Giebel, Sebastian ;
Marks, David, I ;
Boissel, Nicolas ;
Baron, Frederic ;
Chiaretti, Sabina ;
Ciceri, Fabio ;
Cornelissen, Jan J. ;
Doubek, Michael ;
Esteve, Jordi ;
Fielding, Adele ;
Foa, Robin ;
Gorin, Norbert-Claude ;
Gokbuget, Nicola ;
Hallbook, Helene ;
Hoelzer, Dieter ;
Paravichnikova, Elena ;
Ribera, Josep-Maria ;
Savani, Bipin ;
Rijneveld, Anita W. ;
Schmid, Christoph ;
Wartiovaara-Kautto, Ulla ;
Mohty, Mohamad ;
Nagler, Arnon ;
Dombret, Herve .
BONE MARROW TRANSPLANTATION, 2019, 54 (06) :798-809
[4]   Comparable results of autologous and allogeneic haematopoietic stem cell transplantation for adults with Philadelphia-positive acute lymphoblastic leukaemia in first complete molecular remission: An analysis by the Acute Leukemia Working Party of the EBMT [J].
Giebel, Sebastian ;
Labopin, Myriam ;
Potter, Michael ;
Poire, Xavier ;
Sengeloev, Henrik ;
Socie, Gerard ;
Huynh, Anne ;
Afanasyev, Boris V. ;
Schanz, Urs ;
Ringden, Olle ;
Kalhs, Peter ;
Beelen, Dietrich W. ;
Campos, Antonio M. ;
Masszi, Tamas ;
Canaani, Jonathan ;
Mohty, Mohamad ;
Nagler, Arnon .
EUROPEAN JOURNAL OF CANCER, 2018, 96 :73-81
[5]   Allogeneic haematopoietic stem cell transplantation improves outcome of adults with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia entering remission following CD19 chimeric antigen receptor T cells [J].
Gu, Bin ;
Shi, Bing-Yu ;
Zhang, Xiang ;
Zhou, Shi-Yuan ;
Chu, Jian-Hong ;
Wu, Xiao-Jin ;
Fu, Cheng-Cheng ;
Qiu, Hui-Ying ;
Han, Yue ;
Chen, Su-Ning ;
Yu, Lei ;
Ma, Xiao ;
Wu, De-Pei .
BONE MARROW TRANSPLANTATION, 2021, 56 (01) :91-100
[6]   Anti-CD19 chimeric antigen receptor-modified T-cell therapy bridging to allogeneic hematopoietic stem cell transplantation for relapsed/refractory B-cell acute lymphoblastic leukemia: An open-label pragmatic clinical trial [J].
Jiang, Huiwen ;
Li, Chenggong ;
Yin, Ping ;
Guo, Tao ;
Liu, Lin ;
Xia, Linghui ;
Wu, Yaohui ;
Zhou, Fen ;
Ai, Lisha ;
Shi, Wei ;
Lu, Xuan ;
Wang, Huafang ;
Tang, Lu ;
Wei, Qiuzhe ;
Deng, Jun ;
Jin, Runming ;
Xiong, Wei ;
Dong, Jian ;
Mei, Heng ;
Hu, Yu .
AMERICAN JOURNAL OF HEMATOLOGY, 2019, 94 (10) :1113-1122
[7]   Treatment response, survival, safety, and predictive factors to chimeric antigen receptor T cell therapy in Chinese relapsed or refractory B cell acute lymphoblast leukemia patients [J].
Li, Limin ;
Liu, Jie ;
Xu, Mengyuan ;
Yu, Hongjuan ;
Lv, Chengfang ;
Cao, Fenglin ;
Wang, Zhenkun ;
Fu, Yueyue ;
Zhang, Mingwen ;
Meng, Hongbin ;
Zhang, Xiaoqian ;
Kang, Liqing ;
Zhang, Zhuo ;
Li, Jinmei ;
Feng, Jiawei ;
Lian, Xin ;
Yu, Lei ;
Zhou, Jin .
CELL DEATH & DISEASE, 2020, 11 (03)
[8]   Tumor Antigen Escape from CAR T-cell Therapy [J].
Majzner, Robbie G. ;
Mackall, Crystal L. .
CANCER DISCOVERY, 2018, 8 (10) :1219-1226
[9]   CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia [J].
Maude, Shannon L. ;
Teachey, David T. ;
Porter, David L. ;
Grupp, Stephan A. .
BLOOD, 2015, 125 (26) :4017-4023
[10]   Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia [J].
Maude, Shannon L. ;
Frey, Noelle ;
Shaw, Pamela A. ;
Aplenc, Richard ;
Barrett, David M. ;
Bunin, Nancy J. ;
Chew, Anne ;
Gonzalez, Vanessa E. ;
Zheng, Zhaohui ;
Lacey, Simon F. ;
Mahnke, Yolanda D. ;
Melenhorst, Jan J. ;
Rheingold, Susan R. ;
Shen, Angela ;
Teachey, David T. ;
Levine, Bruce L. ;
June, Carl H. ;
Porter, David L. ;
Grupp, Stephan A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (16) :1507-1517
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