Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report

被引:2
作者
Morrison, Chase William [1 ]
Sanjasaz, Kayvon Nick [1 ]
Nathanson, Saul David [2 ,3 ]
Raina-Hukku, Supriya [4 ]
Pinkney, David Matthew [5 ]
Davenport, Alexis Anna [5 ]
机构
[1] Wayne State Univ, Detroit, MI USA
[2] Henry Ford Hlth, Dept Surg, 2799 W Grand Blvd, Detroit, MI 48202 USA
[3] Wayne State Univ Med Sch, 2799 W Grand Blvd, Detroit, MI 48202 USA
[4] Henry Ford Hlth, Dept Otolaryngol, Detroit, MI USA
[5] Henry Ford Hlth Syst, Dept Radiol, Detroit, MI USA
关键词
Case report; Endometrial carcinoma; Immunotherapy; Metastatic carcinoma; Axillary mass; BLOOD-VESSELS; CANCER; TUMOR; EXIT;
D O I
10.1186/s13256-023-04192-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background We present an unusual case of a left axillary lymph node metastasis from a primary dedifferentiated endometrial carcinoma. This pattern of metastasis is likely the result of circulating tumor cells reaching the node through its arterial blood supply. Case presentation In this report, a 68-year-old white woman with a dedifferentiated endometrial carcinoma underwent a hysterectomy. She later developed an enlarged axillary lymph node due to metastatic dedifferentiated endometrial carcinoma, treated with chemotherapy and anti-programmed cell death protein 1 immunotherapy resulting in a complete clinical and radiological response. Conclusion A review of the literature reveals the rarity of blood-borne lymph node metastasis, especially with uterine carcinoma. Immunotherapy has shown promising results in the treatment of some subtypes of metastatic uterine carcinoma.
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页数:7
相关论文
共 33 条
[1]  
Abeler VM, 1996, CANCER, V78, P1740, DOI 10.1002/(SICI)1097-0142(19961015)78:8<1740::AID-CNCR14>3.0.CO
[2]  
2-Y
[3]   Pembrolizumab in endometrial cancer: Where we stand now [J].
Aravantinou-Fatorou, Aikaterini ;
Andrikopoulou, Angeliki ;
Liontos, Michael ;
Fiste, Oraianthi ;
Georgakopoulou, Vasiliki E. ;
Dimopoulos, Meletios-Athanasios ;
Gavriatopoulou, Maria ;
Zagouri, Flora .
ONCOLOGY LETTERS, 2021, 22 (06)
[4]   Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice [J].
Brown, M. ;
Assen, F. P. ;
Leithner, A. ;
Abe, J. ;
Schachner, H. ;
Asfour, G. ;
Bago-Horvath, Z. ;
Stein, J. V. ;
Uhrin, P. ;
Sixt, M. ;
Kerjaschki, D. .
SCIENCE, 2018, 359 (6382) :1408-+
[5]   Non-mammary metastases to the breast and axilla: a study of 85 cases [J].
DeLair, Deborah F. ;
Corben, Adriana D. ;
Catalano, Jeffrey P. ;
Vallejo, Christina E. ;
Brogi, Edi ;
Tan, Lee K. .
MODERN PATHOLOGY, 2013, 26 (03) :343-349
[6]   Current Status of Clinical Trials for Cervical and Uterine Cancer Using Immunotherapy Combined With Radiation [J].
Dyer, Brandon A. ;
Feng, Christine H. ;
Eskander, Ramez ;
Sharabi, Andrew B. ;
Mell, Loren K. ;
McHale, Michael ;
Mayadev, Jyoti S. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2021, 109 (02) :396-412
[7]   Breast metastasis from endometrial clear cell carcinoma: A case report and review of the literature [J].
En Choo, Amadora Li ;
Sim, Llewellyn Shao-jen ;
Sittampalam, Kesavan ;
Tan, Wei Chong ;
En Tay, Amos Zhi ;
Nadarajah, Ravichandran ;
Tan, Veronique Kiak Mien ;
Sim, Yirong .
FRONTIERS IN ONCOLOGY, 2023, 12
[8]  
FOOTE RL, 1988, CANCER-AM CANCER SOC, V61, P2561, DOI 10.1002/1097-0142(19880615)61:12<2561::AID-CNCR2820611229>3.0.CO
[9]  
2-2
[10]   Ovarian, uterine, and cervical cancer patients with distant metastases at diagnosis: most common locations and outcomes [J].
Gardner, Austin B. ;
Charo, Lindsey M. ;
Mann, Amandeep K. ;
Kapp, Daniel S. ;
Eskander, Ramez N. ;
Chan, John K. .
CLINICAL & EXPERIMENTAL METASTASIS, 2020, 37 (01) :107-113