A novel near-infrared fluorescent probe for the imaging of viscosity in cells and tumor-bearing mice

被引:13
作者
Liao, Qin-Ting [1 ]
Chao, Jing-Jing [1 ]
Wang, Wen-Xin [1 ]
Liu, Ting [1 ]
Mao, Guo-Jiang [2 ]
Xu, Fen [1 ]
Li, Chun-Yan [1 ]
机构
[1] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environmentally Friendly Chem,Minist Educ, Xiangtan 411105, Peoples R China
[2] Henan Normal Univ, Collaborat Innovat Ctr Henan Prov Green Mfg Fine C, Henan Key Lab Organ Funct Mol & Drug Innovat, Key Lab Green Chem Media & React,Minist Educ,Sch C, Xinxiang 453007, Peoples R China
基金
中国国家自然科学基金;
关键词
DIAGNOSIS; MOTION;
D O I
10.1039/d3cc01101a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A near-infrared fluorescent probe (IC-V) for detecting viscosity is constructed. The probe has a large Stokes shift (170 nm) and an about 180-fold increase in fluorescence intensity at 700 nm. In addition, IC-V can not only distinguish cancer cells from normal cells, but also monitor viscosity in normal mice and tumor-bearing mice.
引用
收藏
页码:5607 / 5610
页数:4
相关论文
共 44 条
[1]   Microfluidic Diffusion Viscometer for Rapid Analysis of Complex Solutions [J].
Arosio, Paolo ;
Hu, Kevin ;
Aprile, Francesco A. ;
Mueller, Thomas ;
Knowles, Tuomas P. J. .
ANALYTICAL CHEMISTRY, 2016, 88 (07) :3488-3493
[2]   Synthesis, photophysical, viscosity and DFT study of solid state fluorescent molecular rotors [J].
Bhalekar, Sulochana ;
Avhad, Kiran ;
Sekar, Nagaiyan .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2019, 371 :223-237
[3]   SEDIMENTATION BEHAVIOR IN CEMENT PASTES SUBJECTED TO CONTINUOUS SHEAR IN ROTATIONAL VISCOMETERS [J].
BHATTY, JI ;
BANFILL, PFG .
CEMENT AND CONCRETE RESEARCH, 1982, 12 (01) :69-78
[4]   Integrated microfluidic viscometer for edible oil analysis [J].
Bianco, M. ;
Zizzari, A. ;
Gazzera, L. ;
Metrangolo, P. ;
Gigli, G. ;
Viola, I. ;
Arima, V. .
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 265 :91-97
[5]   Near-Infrared in and out: Observation of Autophagy during Strokevia a Lysosome-Targeting Two-Photon Viscosity-Dependent Probe [J].
Chai, Li ;
Liang, Tianyu ;
An, Qian ;
Hu, Wei ;
Wang, Yanying ;
Wang, Baoshuai ;
Su, Shengze ;
Li, Chunya .
ANALYTICAL CHEMISTRY, 2022, 94 (15) :5797-5804
[6]   A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model [J].
Chen, Bochao ;
Mao, Shumei ;
Sun, Yanyan ;
Sun, Liyuan ;
Ding, Ning ;
Li, Chengde ;
Zhou, Jin .
CHEMICAL COMMUNICATIONS, 2021, 57 (36) :4376-4379
[7]   Design of Activatable NIR-II Molecular Probe for In Vivo Elucidation of Disease-Related Viscosity Variations [J].
Dou, Kun ;
Huang, Weijing ;
Xiang, Yunhui ;
Li, Songjiao ;
Liu, Zhihong .
ANALYTICAL CHEMISTRY, 2020, 92 (06) :4177-4181
[8]   Fluorescent probes for the detection of disease-associated biomarkers [J].
Dou, Wei-Tao ;
Han, Hai-Hao ;
Sedgwick, Adam C. ;
Zhu, Guo-Biao ;
Zang, Yi ;
Yang, Xin-Rong ;
Yoon, Juyoung ;
James, Tony D. ;
Li, Jia ;
He, Xiao-Peng .
SCIENCE BULLETIN, 2022, 67 (08) :853-878
[9]   A Mitochondria-Specific Orange/Near-Infrared-Emissive Fluorescent Probe for Dual-Imaging of Viscosity and H2O2 in Inflammation and Tumor Models [J].
Fan, Li ;
Zan, Qi ;
Wang, Xiaodong ;
Wang, Shuohang ;
Zhang, Yuewei ;
Dong, Wenjuan ;
Shuang, Shaomin ;
Dong, Chuan .
CHINESE JOURNAL OF CHEMISTRY, 2021, 39 (05) :1303-1309
[10]   Real-time imaging of acute alcoholic liver injury in vivo via a robust viscosity probe with aggregation-induced emission nature [J].
Feng, Yangzhen ;
Nie, Gang ;
Liang, Wenjie ;
Li, Wanqing ;
Zhang, Yu ;
Wang, Kaiping ;
Chen, Dugang .
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 355