Pathological changes in the brain after peripheral burns

被引：9

作者：

Chen, Jigang ^{[1
]}

Zhang, Danfeng ^{[2
]}

Zhang, Junhui ^{[3
]}

Wang, Yanni ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Dept Burn & Plast Surg, Beijing 100045, Peoples R China

[2] Second Mil Med Univ, Shanghai Changzheng Hosp, Dept Neurosurg, Shanghai 200003, Peoples R China

[3] Third Mil Med Univ, Southwest Hosp, State Key Lab Trauma Burns & Combined Injury, Chongqing 400038, Peoples R China

来源：

BURNS & TRAUMA | 2023年 / 11卷

关键词：

Burn; Brain injuries; Pathological changes; Blood-brain barrier; Inflammation; ADHESION MOLECULE EXPRESSION; NITRIC-OXIDE LEVELS; THERMAL-INJURY; INFLAMMATORY RESPONSE; CEREBRAL MICROCIRCULATION; FLUID RESUSCITATION; BARRIER DYSFUNCTION; ENERGY-EXPENDITURE; LIPID-PEROXIDATION; OXIDATIVE STRESS;

D O I：

10.1093/burnst/tkac061

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Brain injuries are common complications in patients with thermal burns and are associated with unpleasant outcomes. In clinical settings, it was once believed that brain injuries were not major pathological processes after burn, at least in part due to the unavailability of specific clinical manifestations. Burn-related brain injuries have been studied for more than a century, but the underlying pathophysiology has not been completely clarified. This article reviews the pathological changes in the brain following peripheral burns at the anatomical, histological, cytological, molecular and cognitive levels. Therapeutic indications based on brain injury as well as future directions for research have been summarized and proposed.

引用

页数：12

共 156 条

[1]

Ahmed SES, 1999, BURNS, V25, P395

[2]

Ali H, 2019, Ann Burns Fire Disasters, V32, P33

[3]

ANTOON AY, 1972, PEDIATRICS, V50, P609

[4] IL-1β regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program [J].

Argaw, Azeb Tadesse ;

Zhang, Yueting ;

Snyder, Brian J. ;

Zhao, Meng-Liang ;

Kopp, Natalya ;

Lee, Sunhee C. ;

Raine, Cedric S. ;

Brosnan, Celia F. ;

John, Gareth R. .

JOURNAL OF IMMUNOLOGY, 2006, 177 (08) :5574-5584

[5] Psychological consequences of pediatric burns from a child and family perspective: A review of the empirical literature [J].

Bakker, Anne ;

Maertens, Koen J. P. ;

Van Son, Maarten J. M. ;

Van Loey, Nancy E. E. .

CLINICAL PSYCHOLOGY REVIEW, 2013, 33 (03) :361-371

[6] In vivo visualization of cerebral microcirculation in systemic thermal injury [J].

Barone, CM ;

Jimenez, DF ;

Huxley, VH ;

Yang, XF .

JOURNAL OF BURN CARE & REHABILITATION, 2000, 21 (01) :20-25

[7]

Barone M, 1997, ACT NEUR S, V70, P265

[8]

Barone M, 1997, ACT NEUR S, V70, P267

[9] KINETICS OF NITROGEN-OXIDE PRODUCTION FOLLOWING EXPERIMENTAL THERMAL-INJURY IN RATS [J].

BECKER, WK ;

SHIPPEE, RL ;

MCMANUS, AT ;

MASON, AD ;

PRUITT, BA .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1993, 34 (06) :855-862

[10] Emerging experimental therapies for intracerebral hemorrhage: targeting mechanisms of secondary brain injury [J].

Belur, Praveen K. ;

Chang, Jason J. ;

He, Shuhan ;

Emanuel, Benjamin A. ;

Mack, William J. .

NEUROSURGICAL FOCUS, 2013, 34 (05)

← 1 2 3 4 5 6 7 8 9 10 →