The Role of Placental Non-Coding RNAs in Adverse Pregnancy Outcomes

被引：1

作者：

Ren, Jiawen ^{[1
,2
,3
,4
]}

Jin, Heyue ^{[1
,2
,3
,4
]}

Zhu, Yumin ^{[1
,2
,3
,4
]}

机构：

[1] Anhui Med Univ, Sch Publ Hlth, Dept Maternal Child & Adolescent Hlth, 81 Meishan Rd, Hefei 230032, Peoples R China

[2] Anhui Med Univ, Sch Publ Hlth, MOE Key Lab Populat Hlth Life Cycle, 81 Meishan Rd, Hefei 230032, Peoples R China

[3] Anhui Med Univ, Anhui Prov Key Lab Populat Hlth & Aristogen, 81 Meishan Rd, Hefei 230032, Peoples R China

[4] Anhui Med Univ, NHC Key Lab Study Abnormal Gametes & Reprod Tract, Hefei 230032, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 05期

基金：

中国国家自然科学基金;

关键词：

placenta; miRNA; lncRNA; circRNA; adverse pregnancy outcomes; RECURRENT SPONTANEOUS-ABORTION; GESTATIONAL DIABETES-MELLITUS; LOW-BIRTH-WEIGHT; EXPRESSION PROFILE; PRETERM BIRTH; HYPERTENSIVE DISORDERS; FUNCTIONAL ANNOTATION; MESSENGER-RNAS; CIRCULAR RNAS; MICRORNAS;

D O I：

10.3390/ijms24055030

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Non-coding RNAs (ncRNAs) are transcribed from the genome and do not encode proteins. In recent years, ncRNAs have attracted increasing attention as critical participants in gene regulation and disease pathogenesis. Different categories of ncRNAs, which mainly include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in the progression of pregnancy, while abnormal expression of placental ncRNAs impacts the onset and development of adverse pregnancy outcomes (APOs). Therefore, we reviewed the current status of research on placental ncRNAs and APOs to further understand the regulatory mechanisms of placental ncRNAs, which provides a new perspective for treating and preventing related diseases.

引用

页数：23

共 194 条

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