Recent Advances in Functionalization of Aromatic C(sp2)-H Bonds Based on N-Nitroso Direction

In recent years, examples of activation of aromatic C(sp(2))-H bonds successfully constructing C-C bonds and C-heteroatom bonds through N-nitroso synergistic chelation with transition metals have been reported. It is based on the oxidative cleavage of internal N-N bonds, and does not require the addition of external oxidants during the reaction process. After the reaction completion, it can leave on its own, which has made it develop into a new and efficient directing group, and has received widespread attention from researchers. The latest research progress on functionalization of aromatic C(sp(2))-H bonds based on N-nitroso direction is summarized.