Diagnosis and treatment of post-cholecystectomy diarrhoea

被引:3
作者
Huang, Rang-Lang [1 ]
Huang, Wen-Kai [2 ]
Xiao, Xiang-Yi [3 ]
Ma, Lin-Feng [3 ]
Gu, He-Zi-Rui [3 ]
Yang, Guo-Ping [4 ]
机构
[1] Cent South Univ, Dept Hepatobiliary & Pancreat Surg, Xiangya Hosp 3, Changsha 410013, Hunan Province, Peoples R China
[2] Cent South Univ, Dept Gen Med, Xiangya Hosp 3, Changsha 410013, Hunan Province, Peoples R China
[3] Cent South Univ, Xiangya Sch Med, Changsha 410013, Hunan Province, Peoples R China
[4] Cent South Univ, Dept Clin Pharm, Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan Province, Peoples R China
关键词
Cholecystitis; Gallstones; Bile acids; Colon; Bile acid diarrhoea; BILE-ACID MALABSORPTION; PEPTIDE-1 RECEPTOR AGONISTS; PYLORO-DUODENAL MOTILITY; IRRITABLE-BOWEL-SYNDROME; LAPAROSCOPIC CHOLECYSTECTOMY; LIRAGLUTIDE; RISK; SYMPTOMS; OUTCOMES; PATHOPHYSIOLOGY;
D O I
10.4240/wjgs.v15.i11.2398
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The incidence of cholecystitis is relatively high in developed countries and may usually be attributed to gallstones, the treatment for which involves complete surgical removal of the gallbladder (cholecystectomy). Bile acids produced following cholecystectomy continue to flow into the duodenum but are poorly absorbed by the colon. Excessive bile acids in the colon stimulate mucosal secretion of water and electrolytes leading, in severe cases, to diarrhoea. Bile acid diarrhoea (BAD) is difficult to diagnose, requiring a comprehensive medical history and physical examination in combination with laboratory evaluation. The current work reviews the diagnosis and treatment of BAD following cholecystectomy.
引用
收藏
页码:2398 / 2405
页数:8
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