Eco-friendly, green and new metal-free intramolecular Friedel-Crafts reaction to synthesis of Acridones derivatives using phenylboronic acid derivatives

被引：2
作者：
Askarzadeh, Mohammad [1 ]
Moazzam, Ali [2 ]
Sayahi, Mohammad Hosein [3 ]
Fouladvand, Aida [2 ]
Adib, Mehdi [1 ]
Mahdavi, Mohammad [2 ]
机构：
[1] Univ Tehran, Coll Sci, Sch Chem, Tehran, Iran
[2] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran, Iran
[3] Payame Noor Univ PNU, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2023年 / 123卷
关键词：
Acridones; Metal -free intramolecular C -C bond; formation; Carbonylation; Friedel-Crafts reaction; C-H ACTIVATION; CYCLIZATION; LIMITATIONS;
D O I：
10.1016/j.tetlet.2023.154532
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we report a new, facile, versatile metal-free method for preparation of the various Acridones through an intramolecular carbonylation of 2-(phenylamino)benzoic acid derivatives and phenylboronic acid derivatives as activating agent for activation of carboxylic acid group in intramolecular C-C bond formation through Friedel-Crafts reaction. The reaction proceeds under solvent-free conditions, tolerates a wide range of functional groups, and provides rapid access to a range of the Acridones in good to excellent yields.
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页数：5
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