Acceptability of a Combination Adherence Strategy to Support HIV Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence During Pregnancy and Breastfeeding in Malawi

被引:2
作者
Saidi, Friday [1 ,2 ,5 ]
Phanga, Twambilile [1 ]
Graybill, Lauren A. [3 ]
Mollan, Katie R. [3 ]
Hill, Lauren M. [4 ]
Sibande, Watson [1 ]
Msowoya, Getrude [1 ]
Thom, Annie [1 ]
Rosenberg, Nora E. [4 ]
Freeborn, Kellie [5 ]
Amico, K. Rivet [6 ]
Phiri, Sam [7 ]
Mutale, Wilbroad [8 ]
Chi, Benjamin H. [5 ]
机构
[1] Univ North Carolina UNC, Project Malawi, Bag A 104, Lilongwe, Malawi
[2] Kamuzu Univ Hlth Sci, Dept Obstet & Gynecol, Lilongwe, Malawi
[3] Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
[4] Univ North Carolina Chapel Hill, Dept Hlth Behav, Chapel Hill, NC USA
[5] Univ North Carolina Chapel Hill, Sch Med, Dept Obstet & Gynecol, Chapel Hill, NC 27599 USA
[6] Univ Michigan, Dept Hlth Behav & Hlth Educ, Sch Publ Hlth, Ann Arbor, MI USA
[7] Partners Hope, Lilongwe, Malawi
[8] Univ Zambia, Dept Hlth Policy, Sch Publ Hlth, Lusaka, Zambia
关键词
HIV; Antiretroviral drugs; Pre-exposure prophylaxis; Pregnancy and breastfeeding; Mixed methods; WOMEN; INTERVENTIONS;
D O I
10.1007/s10461-023-04116-x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In two parallel pilot studies, we implemented a combination adherence intervention of patient-centered counselling and adherence supporter training, tailored to support HIV treatment (i.e., antiretroviral therapy) or prevention (i.e., pre-exposure prophylaxis, or PrEP) during pregnancy and breastfeeding. Using a mixed-methods approach, we evaluated the intervention's acceptability. We investigated engagement, satisfaction, and discussion content via survey to all 151 participants assigned to the intervention arm (51 women living with HIV, 100 PrEP-eligible women without HIV). We also conducted serial in-depth interviews with a subgroup (n = 40) at enrollment, three months, and six months. In the quantitative analysis, the vast majority reported high satisfaction with intervention components and expressed desire to receive it in the future, if made available. These findings were supported in the qualitative analysis, with favorable comments about counselor engagement, intervention content and types of support received from adherence supporters. Overall, these results demonstrate high acceptability and provide support for HIV status-neutral interventions for antiretroviral adherence.
引用
收藏
页码:4022 / 4032
页数:11
相关论文
共 39 条
  • [1] Integrated Next Step Counseling (iNSC) for Sexual Health and PrEP Use Among Young Men Who Have Sex with Men: Implementation and Observations from ATN110/113
    Amico, K. Rivet
    Miller, Jessica
    Balthazar, Christopher
    Serrano, Pedro Alonso
    Brothers, Jennifer
    Zollweg, Sarah
    Hosek, Sybil
    [J]. AIDS AND BEHAVIOR, 2019, 23 (07) : 1812 - 1823
  • [2] The Information-Motivation-Behavioral Skills Model of ART Adherence in a Deep South HIV plus Clinic Sample
    Amico, K. Rivet
    Barta, William
    Konkle-Parker, Deborah J.
    Fisher, Jeffrey D.
    Cornman, Deborah H.
    Shuper, Paul A.
    Fisher, William A.
    [J]. AIDS AND BEHAVIOR, 2009, 13 (01) : 66 - 75
  • [3] Qualitative methods to ensure acceptability of behavioral and social interventions to the target population
    Ayala, Guadalupe X.
    Elder, John P.
    [J]. JOURNAL OF PUBLIC HEALTH DENTISTRY, 2011, 71 : S69 - S79
  • [4] ROUTINE PRENATAL SCREENING FOR HIV-INFECTION
    BARBACCI, M
    REPKE, JT
    CHAISSON, RE
    [J]. LANCET, 1991, 337 (8743) : 709 - 711
  • [5] Berner-Rodoreda A, 2021, BMC PUBLIC HEALTH, V21, DOI [10.1186/s12889-021-12314-2, 10.1186/s12872-021-02410-x]
  • [6] Integrated Next Step Counseling for Sexual Health Promotion and Medication Adherence for Individuals Using Pre-exposure Prophylaxis
    Chianese, Christopher
    Amico, K. Rivet
    Mayer, Kenneth
    Liu, Albert
    Mcmahan, Vanessa
    Hosek, Sybil
    Mehrotra, Megha
    Grant, Robert
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2014, 30 : A159 - A159
  • [7] Designing and evaluating interventions to eliminate racial and ethnic disparities in health care
    Cooper, LA
    Hill, MN
    Powe, NR
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2002, 17 (06) : 477 - 486
  • [8] Delivering preexposure prophylaxis to pregnant and breastfeeding women in Sub-Saharan Africa: the implementation science frontier
    Davey, Dvora L. Joseph
    Bekker, Linda-Gail
    Gorbach, Pamina M.
    Coates, Thomas J.
    Myer, Landon
    [J]. AIDS, 2017, 31 (16) : 2193 - 2197
  • [9] Early pre-exposure prophylaxis (PrEP) initiation and continuation among pregnant and postpartum women in antenatal care in Cape Town, South Africa
    Davey, Dvora Leah Joseph
    Mvududu, Rufaro
    Mashele, Nyiko
    Lesosky, Maia
    Khadka, Nehaa
    Bekker, Linda-Gail
    Gorbach, Pamina
    Coates, Thomas J.
    Myer, Landon
    [J]. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2022, 25 (02)
  • [10] Delany-Moretlwe S, 2022, LANCET