Eccrine Porocarcinoma of the Vulva With Sarcomatoid Transformation, a New Human Papillomavirus-associated Malignancy? Case Report and Review of the Literature

被引：0

作者：

Campbell, Katelynn ^{[1
,4
]}

Quiroga, Eleonora Fiorletta ^{[2
]}

Dunn, Andrew ^{[3
]}

Zoumberos, Nicholas ^{[2
]}

Quick, Charles Matthew ^{[2
]}

机构：

[1] Univ Saskatchewan, Dept Pathol, Saskatoon, SK, Canada

[2] Univ Arkansas Med Sci, Dept Pathol, Little Rock, AR USA

[3] Hattiesburg Clin, Dept Pathol, Hattiesburg, MS USA

[4] Saskatoon City Hosp, 701 Queen St, Saskatoon, SK S7K 0M7, Canada

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY | 2023年 / 42卷 / 06期

关键词：

Human papillomavirus; Porocarcinoma; Sarcomatoid transformation; Vulva; DIFFERENTIATING POROCARCINOMA; POROMA;

D O I：

10.1097/PGP.0000000000000963

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Eccrine porocarcinoma is a rare cutaneous neoplasm, and rarer still in the anogenital region. In the vulva, the most common carcinoma by far is squamous cell carcinoma; however, eccrine porocarcinoma can arise at this site. As the distinction between porocarcinoma and squamous cell carcinoma has important prognostic implications at other cutaneous sites, it stands to reason that it may have these same implications in the vulva. We present a case of an eccrine porocarcinoma in the vulva of a 70-year-old woman that, in addition, showed sarcomatoid transformation. This tumor harbored human papillomavirus-18 DNA and mRNA, raising the question of the role of the oncogenic virus in sweat gland neoplasms of the vulva.

引用

页码：561 / 566

页数：6

共 26 条

[1] Eccrine Porocarcinoma of the Vulva: A Case Report and Review of Literature [J].

Adegboyega, Patrick A. .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2011, 30 (01) :95-100

[2]

Fujimine-Sato Ayako, 2016, J Med Case Rep, V10, P319

[3] Sarcomatoid eccrine porocarcinoma: report of two cases and a review of the literature [J].

Goh, Seng Geok Nicholas ;

Dayrit, Johannes F. ;

Calonje, Eduardo .

JOURNAL OF CUTANEOUS PATHOLOGY, 2007, 34 (01) :55-60

[4] CD117 (KIT) is a useful immunohistochemical marker for differentiating porocarcinoma from squamous cell carcinoma [J].

Goto, Keisuke ;

Takai, Toshihiro ;

Fukumoto, Takaya ;

Anan, Takashi ;

Kimura, Tetsunori ;

Ansai, Shin-ichi ;

Oshitani, Yoshimi ;

Murata, Yozo ;

Sakuma, Toshiko ;

Hirose, Takanori .

JOURNAL OF CUTANEOUS PATHOLOGY, 2016, 43 (03) :219-226

[5]

Hamza M., 2022, Int J Gynecol Pathol

[6] A large porocarcinoma of perineal region: MR findings and review of the literature [J].

Iannicelli, Elsa ;

Galluzzo, Alessandra ;

Salvi, Pier Federico ;

Ziparo, Vincenzo ;

David, Vincenzo .

ABDOMINAL IMAGING, 2008, 33 (06) :744-747

[7] Vulvar eccrine porocarcinoma [J].

Katsanis, WA ;

Doering, DL ;

Bosscher, JR ;

OConnor, DM .

GYNECOLOGIC ONCOLOGY, 1996, 62 (03) :396-399

[8] Sebaceous differentiation in poroid neoplasms: Report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma) [J].

Kazakov, Dmitry V. ;

Kutzner, Heinz ;

Spagnolo, Dominic V. ;

Kempf, Werner ;

Zelger, Bernhard ;

Mukensnabl, Petr ;

Michal, Michal .

AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2008, 30 (01) :21-26

[9] Biphasic Sarcomatoid Porocarcinoma [J].

Le, Mary D. ;

Hassan, Khaled ;

Cassarino, David S. .

AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2016, 38 (01) :73-76

[10] Eccrine carcinoma (nodular porocarcinoma) of the vulva [J].

Liegl, B ;

Regauer, S .

HISTOPATHOLOGY, 2005, 47 (03) :324-326

← 1 2 3 →