Wearable and flexible electrochemical sensors for sweat analysis: a review

被引：329

作者：

Gao, Fupeng ^{[1
,2
]}

Liu, Chunxiu ^{[1
,2
]}

Zhang, Lichao ^{[1
,2
]}

Liu, Tiezhu ^{[1
,2
]}

Wang, Zheng ^{[1
,2
]}

Song, Zixuan ^{[1
,2
]}

Cai, Haoyuan ^{[1
,2
]}

Fang, Zhen ^{[1
,2
]}

Chen, Jiamin ^{[1
,2
]}

Wang, Junbo ^{[1
,2
]}

Han, Mengdi ^{[3
]}

Wang, Jun ^{[4
]}

Lin, Kai ^{[5
]}

Wang, Ruoyong ^{[5
]}

Li, Mingxiao ^{[6
]}

Mei, Qian ^{[7
]}

Ma, Xibo ^{[8
]}

Liang, Shuli ^{[9
]}

Gou, Guangyang ^{[1
,2
]}

Xue, Ning ^{[1
,2
]}

机构：

[1] Univ Chinese Acad Sci UCAS, Sch Elect Elect & Commun Engn, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Aerosp Informat Res Inst AIR, State Key Lab Transducer Technol, Beijing 100190, Peoples R China

[3] Peking Univ, Coll Future Technol, Dept Biomed Engn, Beijing 100871, Peoples R China

[4] Beijing Shuimujiheng Biotechnol Co, Beijing 101102, Peoples R China

[5] PLA AF Characterist Med Ctr, Beijing 100142, Peoples R China

[6] Chinese Acad Sci, Inst Microelect, Beijing 100029, Peoples R China

[7] Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, CAS Key Lab Biomed Diagnost, Suzhou 215163, Peoples R China

[8] Chinese Acad Sci, Inst Automation, CBSR&NLPR, Beijing, Peoples R China

[9] Capital Med Univ, Beijing Childrens Hosp, Funct Neurosurg Dept, Beijing 100045, Peoples R China

来源：

MICROSYSTEMS & NANOENGINEERING | 2023年 / 9卷 / 01期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

TATTOO SENSOR; URIC-ACID; GLUCOSE; SYSTEM; PH; CHALLENGES; BIOSENSOR; PLATFORM; PLASMA; INTERLEUKIN-6;

D O I：

10.1038/s41378-022-00443-6

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Flexible wearable sweat sensors allow continuous, real-time, noninvasive detection of sweat analytes, provide insight into human physiology at the molecular level, and have received significant attention for their promising applications in personalized health monitoring. Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance, low cost, miniaturization, and wide applicability. Recent developments in soft microfluidics, multiplexed biosensing, energy harvesting devices, and materials have advanced the compatibility of wearable electrochemical sweat-sensing platforms. In this review, we summarize the potential of sweat for medical detection and methods for sweat stimulation and collection. This paper provides an overview of the components of wearable sweat sensors and recent developments in materials and power supply technologies and highlights some typical sensing platforms for different types of analytes. Finally, the paper ends with a discussion of the challenges and a view of the prospective development of this exciting field.

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