A case of Stevens-Johnson syndrome treated with oral cyclosporine

被引:2
作者
Griffith, Victoria [1 ,5 ]
Ramnot, Amanda [2 ]
Resnik, Sydney R. [3 ]
Resnik, Barry I. [3 ,4 ]
机构
[1] Mem Healthcare, Dept Grad Med Educ, Pembroke Pines, FL USA
[2] Univ Miami Jackson Hlth Syst, Dept Internal Med, Miami, FL USA
[3] Univ Miami, Miller Sch Med, Dr Philip Frost Dept Dermatol & Cutaneous Surg, Miami, FL USA
[4] Resnik Skin Inst, Dept Dermatol, Aventura, FL USA
[5] 703 N Flamingo Rd, Pembroke Pines, FL 33028 USA
关键词
Cyclosporine modified; Stevens-Johnson syndrome; toxic epidermal necrolysis; TOXIC EPIDERMAL NECROLYSIS;
D O I
10.4103/jfmpc.jfmpc_1162_23
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respiratory infection, or other viral entities such as cocksackie A, roseola, or herpes simplex virus. We recommend initiating cyclosporine modified treatment, especially in children, upon any suspicion of SJS/TEN in a patient in order to halt the disease progression as early as possible.
引用
收藏
页码:3425 / 3428
页数:4
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