Sex-Related Variations in the Brain Motor-Network Connectivity at Rest during Puberty

被引:0
作者
Pacheco-Blas, Lucero [1 ]
Gonzalez-Gonzalez, Gabriela [1 ]
Ortega-Aguilar, Alicia [1 ]
机构
[1] Univ Nacl Autonoma Mexico, Fac Med, Dept Bioquim, Ave Univ 3000, Coyoacan 04510, Mexico
来源
APPLIED SCIENCES-BASEL | 2023年 / 13卷 / 18期
关键词
motor cortex; puberty; connectivity; sex-variations; graph theory; ANTERIOR CINGULATE CORTEX; HUMAN CEREBELLUM; ARCHITECTURE; AREAS; PROLIFERATION; OPTIMIZATION; REGISTRATION; MECHANISM; SELECTION; ROBUST;
D O I
10.3390/app131810006
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The development of functional neuroimaging technologies has resulted in a flood of mathematical models that investigate functional brain connections in health and disease. Motor network activity in the resting state and its response to puberty remains to be investigated. Variations between sexes in puberty may appear not just in brain regions involved in sexual and emotional activities, but also in cognitive and motor abilities that are active even when the individual is resting. The aim of this study was to investigate the interactions of the motor subnetwork in the resting state of healthy males and females aged 12 and 16. This study used the OpenNeuro Dataset ds004169:1.0.7, Queensland Twin IMaging. The MRI signals were preprocessed to get adjacency matrices from the sensory/somatomotor and cerebellar networks in the Power atlas. Network topology was analyzed using the centrality measures of strength, hubness, and leverage. The strength of the nodes increases with age in both sex groups. Both sexes had right hemisphere dominance in the cerebellar-mouth subnetwork and left dominance in the cerebellar-hand subnetwork. Eleven leverage centrality regions were common to all groups, the most relevant were the Precuneus, the cingulum postcentral and the supplementary motor area. In both sexes, hubs at age 12 were detected only in the right hemisphere. This dominance was reduced at age 16. Understanding connectivity changes in the brain during rest may enable the identification of neurophysiological mechanisms of cognitive and behavioral development that may contribute to long-term psychological well-being in adolescents.
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页数:22
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共 60 条
  • [1] A QUANTITATIVE STUDY OF THE HUMAN CEREBELLUM WITH UNBIASED STEREOLOGICAL TECHNIQUES
    ANDERSEN, BB
    KORBO, L
    PAKKENBERG, B
    [J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1992, 326 (04) : 549 - 560
  • [2] The architecture of complex weighted networks
    Barrat, A
    Barthélemy, M
    Pastor-Satorras, R
    Vespignani, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (11) : 3747 - 3752
  • [3] A component based noise correction method (CompCor) for BOLD and perfusion based fMRI
    Behzadi, Yashar
    Restom, Khaled
    Liau, Joy
    Liu, Thomas T.
    [J]. NEUROIMAGE, 2007, 37 (01) : 90 - 101
  • [4] Hormone Changes in Peripubertal Girls
    Biro, Frank M.
    Pinney, Susan M.
    Huang, Bin
    Baker, Erin R.
    Chandler, Donald Walt
    Dorn, Lorah D.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (10) : 3829 - 3835
  • [5] The social brain in adolescence
    Blakemore, Sarah-Jayne
    [J]. NATURE REVIEWS NEUROSCIENCE, 2008, 9 (04) : 267 - 277
  • [6] Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review
    Buyanova, Irina S.
    Arsalidou, Marie
    [J]. FRONTIERS IN HUMAN NEUROSCIENCE, 2021, 15
  • [7] Anterior cingulate cortex and conflict detection: An update of theory and data
    Carter, Cameron S.
    van Veen, Vincent
    [J]. COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE, 2007, 7 (04) : 367 - 379
  • [8] Proliferation and death of oligodendrocytes and myelin proteins are differentially regulated in male and female rodents
    Cerghet, M
    Skoff, RP
    Bessert, D
    Zhang, Z
    Mullins, C
    Ghandour, MS
    [J]. JOURNAL OF NEUROSCIENCE, 2006, 26 (05) : 1439 - 1447
  • [9] Neuronal regulation: A mechanism for synaptic pruning during brain maturation
    Chechik, G
    Meilijson, I
    Ruppin, E
    [J]. NEURAL COMPUTATION, 1999, 11 (08) : 2061 - 2080
  • [10] Developmental maturation of inhibitory control circuitry in a high-risk sample: A longitudinal fMRI study
    Cope, Lora M.
    Hardee, Jillian E.
    Martz, Meghan E.
    Zucker, Robert A.
    Nichols, Thomas E.
    Heitzeg, Mary M.
    [J]. DEVELOPMENTAL COGNITIVE NEUROSCIENCE, 2020, 43