Computed Tomography Evaluation of the Paranasal Sinuses in Adults with Primary Ciliary Dyskinesia

被引:5
作者
Plantier, Diogo Barreto [1 ]
Pilan, Renata R. M. [1 ]
Athanazio, Rodrigo [2 ]
Olm, Mary Anne K. [3 ]
Gebrim, Eloisa M. S. [4 ]
Voegels, Richard Louis [1 ]
机构
[1] Univ Sao Paulo, Fac Med, Dept Otorhinolaringol & Ophthalmol, Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Fac Med, Heart Inst, Pulm Div, Sao Paulo, SP, Brazil
[3] Univ Sao Paulo, Fac Med, Dept Pathol, Sao Paulo, SP, Brazil
[4] Univ Sao Paulo, Fac Med, Dept Radiol, Sao Paulo, SP, Brazil
关键词
aplasia; computed tomography scanner; Kartagener syndrome; paranasal sinuses; primary ciliary dyskinesia; CHRONIC RHINOSINUSITIS; CONSENSUS STATEMENT; MANIFESTATIONS; MAXILLARY; MUCOCELE; TOOL;
D O I
10.1055/s-0042-1749392
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Introduction Primary ciliary dyskinesia is a rare inherited disease that results in a malfunction of mucociliary clearance and sinonasal complaints. Aplasia/hypoplasia of the frontal and sphenoid sinuses has been described as more frequent in this population. However, to date, no studies have provided a detailed description of computed tomography findings in adult patients with a diagnosis of this condition. Objective To describe the computed tomography (CT) findings of adult patients with primary ciliary dyskinesia. Methods Retrospective observational study of adult patients with primary ciliary dyskinesia who underwent CT. Results Twenty-one adults were included in the study. Aplasia occurred in 38.1% of frontal sinuses and in 14.3% of sphenoid sinuses. Likewise, hypoplasia occurred in 47.6% of the frontal sinuses, in 54.8% of the sphenoid sinuses and in 40.5% of the maxillary sinuses. Furthermore, trabecular loss was identified in 61.9% ethmoidal sinuses. The mean Lund-Mackay score was 13.5. In addition, 9.5% of the patients had concha bullosa, 47.6% had marked bilateral inferior turbinate hypertrophy, 38.1% had marked middle turbinate hypertrophy, and 47.6% had marked septal deviation. Finally, we identified images suggestive of fungus ball, mucocele, osteoma, a possible antrochoanal polyp, and frontal bone erosions. Conclusion The present study provides a detailed description of CT findings in patients with primary ciliary dyskinesia. We also describe abnormalities that must be identified for safer surgical planning and that suggest a diagnosis of primary ciliary dyskinesia if found in patients with a consistent clinical picture.
引用
收藏
页码:130 / 137
页数:8
相关论文
共 33 条
[1]   Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia [J].
Alanin, Mikkel Christian ;
Aanaes, Kasper ;
Hoiby, Niels ;
Pressler, Tania ;
Skov, Marianne ;
Nielsen, Kim Gjerum ;
Johansen, Helle Krogh ;
von Buchwald, Christian .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2017, 7 (03) :240-247
[2]   Primary ciliary dyskinesia: a consensus statement on diagnostic and treatment approaches in children [J].
Barbato, A. ;
Frischer, T. ;
Kuehni, C. E. ;
Snijders, D. ;
Azevedo, I. ;
Baktai, G. ;
Bartoloni, L. ;
Eber, E. ;
Escribano, A. ;
Haarman, E. ;
Hesselmar, B. ;
Hogg, C. ;
Jorissen, M. ;
Lucas, J. ;
Nielsen, K. G. ;
O'Callaghan, C. ;
Omran, H. ;
Pohunek, P. ;
Strippoli, M-P. F. ;
Bush, A. .
EUROPEAN RESPIRATORY JOURNAL, 2009, 34 (06) :1264-1276
[3]   Paranasal sinuses in children: size evaluation of maxillary, sphenoid, and frontal sinuses by magnetic resonance imaging and proposal of volume index percentile curves [J].
Barghouth, G ;
Prior, JO ;
Lepori, D ;
Duvoisin, B ;
Schnyder, P ;
Gudinchet, F .
EUROPEAN RADIOLOGY, 2002, 12 (06) :1451-1458
[4]   PICADAR: a diagnostic predictive tool for primary ciliary dyskinesia [J].
Behan, Laura ;
Dimitrov, Borislav D. ;
Kuehni, Claudia E. ;
Hogg, Claire ;
Carroll, Mary ;
Evans, Hazel J. ;
Goutaki, Myrofora ;
Harris, Amanda ;
Packham, Samantha ;
Walker, Woolf T. ;
Lucas, Jane S. .
EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (04) :1103-1112
[5]  
Bequignon E., 2019, J CLIN MED, V8, P1
[6]   Ethmoid Mucocele: A New Feature of Primary Ciliary Dyskinesia [J].
Berlucchi, Marco ;
Maroldi, Roberto ;
Aga, Alfred ;
Grazzani, Livia ;
Padoan, Rita .
PEDIATRIC PULMONOLOGY, 2010, 45 (02) :197-201
[7]   Rhinosinusitis in Pediatric Primary Ciliary Dyskinesia: Impact of Disease [J].
Bhatt, Jay M. ;
Muhonen, Ethan G. ;
Meier, Maxene ;
Sagel, Scott D. ;
Chan, Kenny H. .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2019, 161 (05) :877-880
[8]   Anatomic variations of the paranasal sinuses in the general pediatric population [J].
Cohen, Oded ;
Adi, Meital ;
Shapira-Galitz, Yael ;
Halperin, Doron ;
Warman, Meir .
RHINOLOGY, 2019, 57 (03) :206-212
[9]  
Pilan RRD, 2012, RHINOLOGY, V50, P129, DOI [10.4193/Rhin11.256, 10.4193/Rhino11.256]
[10]   CT characterization of developmental variations of the paranasal sinuses in cystic fibrosis [J].
Eggesbo, HB ;
Sovik, S ;
Dolvik, S ;
Eiklid, K ;
Kolmannskog, F .
ACTA RADIOLOGICA, 2001, 42 (05) :482-493