Amelioration of trichotillomania with onabotulinumtoxinA for chronic migraine

被引:1
作者
Engel, Emily Rubenstein [1 ]
Ham, Jeremy-Ann [2 ]
机构
[1] Scripps Clin, Dept Neurol, La Jolla, CA 92037 USA
[2] Scripps Green Hosp, Dept Med, La Jolla, CA USA
关键词
Botulinum toxin; Neurology (drugs and medicines); Psychiatry (drugs and medicines); Headache (including migraines); Anxiety disorders (including OCD and PTSD);
D O I
10.1136/bcr-2022-254006
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report a case of a woman in her 30s who struggled with a life-long history of trichotillomania (TTM; hair-pulling disorder), which was unsuccessfully treated with behavioural therapy and selective serotonin reuptake inhibitors. In addition to TTM, our patient had a history of chronic migraine which brought her to our clinic, and treatment with onabotulinumtoxinA (OBTA) was initiated per the Phase III REsearch Evaluating Migraine Prophylaxis Therapy protocol. After experiencing improvement with migraine symptoms, she began off-label treatment with OBTA for her TTM with 45 units being injected, 5 units per site, in diffuse regions of her scalp, primarily on the affected areas of TTM-induced alopecia. The patient reported marked improvement in her TTM signs and symptoms, which resulted in hair regrowth as early as the first follow-up visit 12 weeks post-treatment initiation. Treatment effects were maintained, and additional hair regrowth was observed at the 1-year post-treatment visit, which equated to four cycles of treatment.
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页数:3
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