Two new sesquiterpenoids from the roots of Sarcandra glabra

被引：3

作者：

Chen, Zhenhao ^{[1
]}

Sun, Yunpeng ^{[1
]}

Wang, Yongyue ^{[1
]}

Kong, Lingyi ^{[1
]}

Luo, Jun ^{[1
]}

机构：

[1] China Pharmaceut Univ, Dept Nat Med Chem, State Key Lab Nat Med, Nanjing, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2023年 / 37卷 / 20期

基金：

中国国家自然科学基金;

关键词：

Sesquiterpenoids; Sarcandra glabra; ECD calculations; DIMERS; SEEDS;

D O I：

10.1080/14786419.2022.2089670

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new sesquiterpenoids, sarglanoids G and H (1 and 2), together with two known analogues (3-4) were isolated from the roots of Sarcandra glabra. Compound 2 was a rare elemene-type sesquiterpenoid with a furan ring fragment, which is mostly lactone ring in its analogues. The structures of new compounds were determined on the basis of extensive spectroscopic methods including HR-ESI-MS, 1D and 2D NMR, and the absolute configuration of 1 was established by ECD calculations. Their anti-inflammatory activities were also evaluated.

引用

页码：3505 / 3511

页数：7

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