Advances in tumor immune microenvironment of head and neck squamous cell carcinoma: A review of literature

被引：6

作者：

Hong, Qichao ^{[1
]}

Ding, Shun ^{[2
]}

Xing, Chengliang ^{[2
]}

Mu, Zhonglin ^{[2
]}

机构：

[1] Hainan Med Univ, Hainan Gen Hosp, Dept Otorhinolaryngol Head & Neck Surg, Hainan Affiliated Hosp, Haikou, Peoples R China

[2] Hainan Med Univ, Affiliated Hosp 1, Dept Otolaryngol Head & Neck Surg, Haikou 570102, Peoples R China

来源：

MEDICINE | 2024年 / 103卷 / 09期

基金：

中国国家自然科学基金;

关键词：

head and neck cancers; immune cells; immune checkpoint; immunotherapy; literature review; tumor microenvironment; POOR-PROGNOSIS; T-CELLS; CLINICAL-RELEVANCE; DENDRITIC CELLS; CANCER; PREDICTS; METASTASIS; CHECKPOINT; EXPRESSION; SURVIVAL;

D O I：

10.1097/MD.0000000000037387

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Squamous cell carcinoma is seen as principal malignancy of head and neck. Tumor immune microenvironment plays a vital role in the occurrence, development and treatment of head and neck squamous cell carcinoma (HNSCC). The effect of immunotherapy, in particular, is closely related to tumor immune microenvironment. This review searched for high-quality literature included within PubMed, Web of Science, and Scopus using the keywords "head and neck cancers," "tumor microenvironment" and "immunotherapy," with the view to summarizing the characteristics of HNSCC immune microenvironment and how various subsets of immune cells promote tumorigenesis. At the same time, based on the favorable prospects of immunotherapy having been shown currently, the study is committed to pinpointing the latest progress of HNSCC immunotherapy, which is of great significance in not only further guiding the diagnosis and treatment of HNSCC, but also conducting its prognostic judgement.

引用

页数：8

共 104 条

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