Anlotinib combined with radiotherapy and chemotherapy for recurrent pelvic osteosarcoma treatment: a case report and literature review

被引:3
作者
Chen, Qian [1 ]
Zheng, Kai [1 ]
Xu, Ming [1 ]
Yan, Ning [2 ]
Hai, Gong [2 ]
Yu, Xiuchun [1 ]
机构
[1] 960th Hosp Peoples Liberat Army, Dept Orthoped, Jinan, Shandong, Peoples R China
[2] 960th Hosp Peoples Liberat Army, Dept Radiotherapy, Jinan, Shandong, Peoples R China
关键词
recurrent pelvis osteosarcoma; anlotinib; radiotherapy; adjuvant chemotherapy; case report; RADIATION-THERAPY; EXPERIENCE;
D O I
10.3389/fonc.2023.1283932
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
At present, the treatment of recurrent pelvic osteosarcoma is too simple, and most of the patients are treated with chemotherapy, radiotherapy, and/or combined surgery. Here, we report a 29-year-old man diagnosed with local recurrent pelvic osteosarcoma. Imaging showed that the tumor had obvious enhancement and abundant blood vessels. There was no indication of surgery. After the patient's consent was obtained, we used anlotinib as a sequential treatment to chemotherapy. During the first course of adjuvant chemotherapy, we treated the patient with intensity-modulated radiotherapy (IMRT) with a total dose of 60 Gy equivalents. No disease recurrence was reported at 25 months after multimodal combination therapy.
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页数:6
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