Effect of virgin coconut oil on body weight, white fat depots, and biochemical and morphological parameters in mice fed standard or high-fat diets

被引：0

作者：

da Silva, Aline Almeida ^{[1
]}

da Silva Perez, Elisangela Martins ^{[2
]}

Tavares de Figueiredo, Ingrid Samantha ^{[1
]}

Nunes de Alencar, Nylane Maria ^{[1
]}

Negreiros Nunes Alves, Ana Paula ^{[1
]}

Narciso Fernandes, Fabiano Andre ^{[1
]}

Vasconcelos, Renata Prado ^{[3
]}

de Oliveira, Ariclecio Cunha ^{[3
]}

Frota Gaban, Socorro Vanesca ^{[1
]}

机构：

[1] Univ Fed Ceara, Fortaleza, Brazil

[2] Univ Ctr Estacio Sa, Via Corpvs, Fortaleza, Brazil

[3] Univ Estadual Ceara, Fortaleza, Brazil

来源：

FOOD & FUNCTION | 2023年 / 14卷 / 15期

关键词：

ADIPOSE-TISSUE; OBESITY; RATS;

D O I：

10.1039/d3fo01447a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This study investigated the effects of virgin coconut oil (VCO) on body weight, white fat depots, and biochemical and morphological parameters in male Swiss mice fed standard (SD) or high-fat (HFD) diets. Thirty-three adult animals were assigned to one of four groups, as follows: SD, SD plus VCO (SDCO), HFD, and HFD plus VCO (HFDCO). VCO had no effects on the Lee index, subcutaneous fat, periepididymal fat, retroperitoneal fat, area under the curve for glucose, or pancreas weight, all of which were increased by HFD. Low-density lipoprotein cholesterol increased in the SDCO group compared with the SD group and decreased in the HFDCO group compared with the HFD group. VCO increased total cholesterol only in the SDCO group compared with the SD group, with no differences between the HFD and HFDCO groups. In conclusion, low-dose VCO supplementation did not improve obesity, had no effects on hepatic or renal function, and had beneficial effects on the lipid profile only in animals fed HFD.

引用

页码：6853 / 6863

页数：11

共 40 条

[11] Health effects of coconut oil: Summary of evidence from systematic reviews and meta-analysis of interventional studies [J].